Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5399375 | 0.79 | ALDH1A1 (0.51) | KDM4EALDH1A1SMN1; SMN2HPGDPTGS1 | |
| SCHEMBL31724069 | 0.76 | KDM4E (0.52) | KDM4EALDH1A1SMN1; SMN2HPGDPTGS1 | |
| SCHEMBL30841426 | 0.73 | KDM4E (0.50) | KDM4EALDH1A1SMN1; SMN2HPGDBACE1 | |
| SCHEMBL3821774 | 0.71 | PTGS2 (0.71) | PTGS1PTGS2 | |
| SCHEMBL11721244 | 0.69 | ALDH1A1 (0.45) | KDM4EALDH1A1SMN1; SMN2HPGDBACE1 | |
| SCHEMBL2721721 | 0.69 | BACE1 (0.53) | KDM4EALDH1A1SMN1; SMN2HPGDBACE1 | |
| SCHEMBL17480605 | 0.69 | ME2 (0.50) | KDM4EALDH1A1SMN1; SMN2HPGDBACE1 | |
| SCHEMBL11084887 | 0.69 | ALDH1A1 (0.46) | KDM4EALDH1A1SMN1; SMN2HPGDBACE1 | |
| SCHEMBL2622585 | 0.69 | PTGS2 (0.68) | KDM4EALDH1A1SMN1; SMN2HPGDBACE1 | |
| SCHEMBL5399372 | 0.67 | PGR (0.41) | KDM4EALDH1A1SMN1; SMN2HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250346550-A1 | METHODS OF MODULATING ENDONUCLEASE G USING RESVERATROL AND ITS DERIVATIVES | UNIV COLORADO REGENTS (US) | 2025-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250346550-A1 | METHODS OF MODULATING ENDONUCLEASE G USING RESVERATROL AND ITS DERIVATIVES | ENDOD1, FEN1, RNASE1 | KDM4E 1565/4885ALDH1A1 3966/4885SMN1; SMN2 2648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.