Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 5/20 | 1.00 |
| ▸ | RXRB | P28702 | 5/20 | 1.00 |
| ▸ | MAOB | P27338 | 1/20 | 0.73 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.72 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.72 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.72 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.68 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.67 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.67 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.66 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.62 |
| ▸ | PTPRC | P08575 | 1/20 | 0.62 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.62 |
| ▸ | PPARA | Q07869 | 1/20 | 0.61 |
| ▸ | APP | P05067 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24488963 | 1.00 | RXRA (1.00) | RXRARXRBMAOBNR4A2NR4A1 | |
| SCHEMBL8134318 | 0.91 | NR4A2 (0.85) | RXRARXRBNR4A2NR4A1NR4A3 | |
| SCHEMBL27704685 | 0.85 | RXRA (0.74) | RXRARXRBMAOBNR4A2NR4A1 | |
| SCHEMBL16395775 | 0.85 | MAOB (1.00) | RXRARXRBMAOBSMN1; SMN2FFAR1 | |
| SCHEMBL3170471 | 0.85 | RXRA (0.73) | RXRARXRBMAOBNR4A2NR4A1 | |
| SCHEMBL228477 | 0.84 | NR4A2 (1.00) | RXRARXRBMAOBNR4A2NR4A1 | |
| SCHEMBL6830467 | 0.84 | NR4A2 (1.00) | RXRARXRBMAOBNR4A2NR4A1 | |
| SCHEMBL4059143 | 0.84 | NR4A2 (1.00) | RXRARXRBMAOBNR4A2NR4A1 | |
| SCHEMBL1750167 | 0.84 | NR4A2 (0.86) | RXRARXRBNR4A2NR4A1NR4A3 | |
| SCHEMBL8067849 | 0.83 | SRD5A2 (0.77) | RXRARXRBMAOBNR4A2NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680150-B2 | Small molecule hematopoietic growth factor mimetic compounds that activate hematopoietic growth factor receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2014-03-25 | — | — | US | disclosed |
| US-20110003851-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS THAT ACTIVATE HEMATOPOIETIC GROWTH FACTOR RECEPTORS | LIGAND PHARMACEUTICALS, INC. (US) | 2011-01-06 | — | — | US | disclosed |
| US-7718087-B2 | Organic iridium compositions and their use in electronic devices | GENERAL ELECTRIC COMPANY (US) | 2010-05-18 | — | — | US | disclosed |
| US-7718277-B2 | Electronic devices comprising organic iridium compositions | GENERAL ELECTRIC COMPANY (US) | 2010-05-18 | — | — | US | disclosed |
| US-7704610-B2 | organic light emitting device comprising deuterated organic iridium complex; optoelectronic devices, photovoltaic devices; enhanced color properties and light output efficiencies | GENERAL ELECTRIC COMPANY (US) | 2010-04-27 | — | — | US | disclosed |
| US-20100090586-A1 | ELECTRONIC DEVICES COMPRISING ORGANIC IRIDIUM COMPOSITIONS | GENERAL ELECTRIC COMPANY | 2010-04-15 | — | — | US | disclosed |
| US-7695640-B2 | Organic iridium compositions and their use in electronic devices | GENERAL ELECTRIC COMPANY (US) | 2010-04-13 | — | — | US | disclosed |
| US-7691292-B2 | organic light emitters; photovoltaic cells; electrophosphorescent | GENERAL ELECTRIC COMPANY (US) | 2010-04-06 | — | — | US | disclosed |
| US-7691494-B2 | Electronic devices comprising organic iridium compositions | GENERAL ELECTRIC COMPANY (US) | 2010-04-06 | — | — | US | disclosed |
| US-20100051869-A1 | ORGANIC IRIDIUM COMPOSITIONS AND THEIR USE IN ELECTRONIC DEVICES | GENERAL ELECTRIC COMPANY | 2010-03-04 | — | — | US | disclosed |
| US-7608677-B2 | Method for preparing polymeric organic iridium compositions | GENERAL ELECTRIC COMPANY (US) | 2009-10-27 | — | — | US | disclosed |
| CN-101535324-A | Organic iridium compositions and their use in electronic devices | GEN ELECTRIC (US) | 2009-09-16 | — | — | CN | disclosed |
| EP-2049555-A2 | ORGANIC IRIDIUM COMPOSITIONS AND THEIR USE IN ELECTRONIC DEVICES | GENERAL ELECTRIC COMPANY (US) | 2009-04-22 | — | — | EP | disclosed |
| US-20080023672-A1 | Organic iridium compositions and their use in electronic devices | GENERAL ELECTRIC COMPANY | 2008-01-31 | — | — | US | disclosed |
| US-20080026249-A1 | Electronic devices comprising organic iridium compositions | GENERAL ELECTRIC COMPANY | 2008-01-31 | — | — | US | disclosed |
| US-20080026250-A1 | Electronic devices comprising organic iridium compositions | GENERAL ELECTRIC COMPANY | 2008-01-31 | — | — | US | disclosed |
| US-20080023671-A1 | Organic iridium compositions and their use in electronic devices | GENERAL ELECTRIC COMPANY | 2008-01-31 | — | — | US | disclosed |
| US-20080027028-A1 | Ketopyrroles useful as ligands in organic iridium compositions | GENERAL ELECTRIC COMPANY | 2008-01-31 | — | — | US | disclosed |
| WO-2008014037-A2 | ORGANIC IRIDIUM COMPOSITIONS AND THEIR USE IN ELECTRONIC DEVICES | GENERAL ELECTRIC COMPANY (US) | 2008-01-31 | — | — | WO | disclosed |
| US-20080026477-A1 | Method for preparing polymeric organic iridium compositions | GENERAL ELECTRIC COMPANY (US) | 2008-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027028-A1 | Ketopyrroles useful as ligands in organic iridium compositions | OR10J3, OPRD1, OCIAD1 | RXRA 618/4885RXRB 717/4885MAOB 2262/4885 |
| US-20110003851-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS THAT ACTIVATE HEMATOPOIETIC GROWTH FACTOR RECEPTORS | MPL, CSF3R, CSF1R | RXRA 650/4885RXRB 743/4885MAOB 4672/4885 |
| US-20100051869-A1 | ORGANIC IRIDIUM COMPOSITIONS AND THEIR USE IN ELECTRONIC DEVICES | OCIAD1, OCIAD2, OXER1 | RXRA 2249/4885RXRB 2309/4885MAOB 2123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.