Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 7/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 7/20 | 0.40 |
| ▸ | CDK1 | P06493 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.39 |
| ▸ | CDK4 | P11802 | 2/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CCR4 | P51679 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25243394 | 1.00 | KDR (0.44) | KDRAURKAAURKBCDK2CDK1 | |
| SCHEMBL25205981 | 0.84 | CDK2 (0.46) | KDRCDK2CDK1NPSR1TP53 | |
| SCHEMBL30397985 | 0.80 | SDHB (0.46) | KDRCDK2CDK1LMNAHPGD | |
| SCHEMBL25239800 | 0.80 | SDHB (0.46) | KDRCDK2CDK1LMNAHPGD | |
| SCHEMBL25527480 | 0.80 | CDK1 (0.64) | KDRCDK2CDK1LRRK2CDK4 | |
| SCHEMBL24087394 | 0.80 | SDHB (0.39) | KDRCDK2CDK1SMN1; SMN2LMNA | |
| SCHEMBL29141591 | 0.77 | TLR9 (0.39) | KDRCDK2CDK1SMN1; SMN2LMNA | |
| SCHEMBL7377255 | 0.76 | LMNA (0.44) | SMN1; SMN2LMNANPSR1KDM4ETP53 | |
| SCHEMBL6042880 | 0.76 | KMT2A (0.45) | SMN1; SMN2LMNAHPGDNPSR1KDM4E | |
| SCHEMBL22400987 | 0.75 | LMNA (0.43) | KDRCDK2CDK1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235261-A1 | BIFUNCTIONAL COMPOUNDS CONTAINING 2,4,5-SUBSTITUTED PYRIMIDINE DERIVATIVES FOR DEGRADING CERTAIN CYCLIN-DEPENDENT KINASE VIA UBIQUITIN PROTEASOME PATHWAY | NIKANG THERAPEUTICS, INC. (US) | 2025-11-13 | — | — | WO | disclosed |