Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | HCK | P08631 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31727906 | 0.83 | DRD2 (0.36) | SRCABL1DRD2HTR7HTR6 | |
| SCHEMBL31727946 | 0.83 | DRD2 (0.36) | SRCABL1DRD2HTR7HTR6 | |
| SCHEMBL31729160 | 0.76 | MET (0.33) | SRCABL1EPHB4PIK3CDEGFR | |
| SCHEMBL31729128 | 0.73 | PTPN11 (0.35) | PTPN11 | |
| SCHEMBL31727720 | 0.72 | EPHB4 (0.33) | SRCABL1DRD2HTR7HTR6 | |
| SCHEMBL31728979 | 0.71 | SRC (0.39) | SRCABL1PIK3CDEGFRKDR | |
| SCHEMBL31728350 | 0.71 | SRC (0.39) | SRCABL1PIK3CDEGFRKDR | |
| SCHEMBL31728564 | 0.71 | CNR1 (0.32) | SRCABL1EPHB4PIK3CDEGFR | |
| SCHEMBL31728000 | 0.67 | NUDT1 (0.43) | PTPN11NUDT1EPHB4 | |
| SCHEMBL31728800 | 0.66 | CRHR1 (0.39) | SRCABL1EPHB4PIK3CDEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |