Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | VEGFA | P15692 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.40 |
| ▸ | SKP1 | P63208 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19013075 | 0.89 | GRM5 (0.45) | GRM5CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL23922807 | 0.83 | GRM5 (0.51) | GRM5CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL949354 | 0.82 | CHRM2 (0.47) | CHRM2CHRM4CHRM1CHRM3KDM4E | |
| SCHEMBL465791 | 0.82 | CHRM2 (0.47) | CHRM2CHRM4CHRM1CHRM3KDM4E | |
| SCHEMBL16061780 | 0.82 | FAAH (0.58) | CHRM2CHRM4CHRM1CHRM3KDM4E | |
| SCHEMBL25282066 | 0.81 | CHRM4 (0.46) | CHRM2CHRM4CHRM1CHRM3KDM4E | |
| SCHEMBL22769224 | 0.81 | CHRM2 (0.46) | GRM5CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL22166944 | 0.80 | ACHE (0.48) | CHRM2CHRM4CHRM1CHRM3KDM4E | |
| SCHEMBL28649806 | 0.77 | MEN1 (0.46) | CHRM2CHRM4CHRM1CHRM3VEGFA | |
| SCHEMBL21237847 | 0.77 | GPR119 (0.44) | CHRM2CHRM4CHRM1CHRM3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250354195-A1 | METHOD OF SCREENING | UNIV DUNDEE (GB) | 2025-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250354195-A1 | METHOD OF SCREENING | PAICS, COASY, ABCG2 | GRM5 4422/4885CHRM2 4215/4885CHRM4 4363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.