SCHEMBL31731982

SCHEMBL31731982

COCc1cc(CCN)c(OC)cc1Br

nearest known ligand 0.70

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 9/20 0.70
HTR2C P28335 7/20 0.70
TAAR1 Q96RJ0 5/20 0.70
HTR2B P41595 5/20 0.48
ADRA1A P35348 1/20 0.47
HTR1A P08908 1/20 0.47
ADRA2A P08913 1/20 0.47
ADRA2B P18089 1/20 0.47
ADRA2C P18825 1/20 0.47
HTR1B P28222 1/20 0.47
HTR7 P34969 1/20 0.47
HTR6 P50406 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24959990 0.85 HTR2A (0.68) HTR2AHTR2CTAAR1HTR2BADRA1A
SCHEMBL29351348 0.82 HTR2A (1.00) HTR2AHTR2CTAAR1HTR2B
SCHEMBL23478 0.82 HTR2A (1.00) HTR2AHTR2CTAAR1HTR2B
SCHEMBL5809547 0.82 HTR2A (1.00) HTR2AHTR2CTAAR1HTR2B
Hydrochloric Acid SCHEMBL22614747 0.81 HTR2A (0.96) HTR2AHTR2CTAAR1HTR2B
Methane SCHEMBL20703126 0.81 HTR2A (0.96) HTR2AHTR2CTAAR1HTR2B
Hydrochloric Acid SCHEMBL25285317 0.81 HTR2A (0.96) HTR2AHTR2CTAAR1HTR2B
SCHEMBL31456014 0.81 HTR2A (0.66) HTR2AHTR2CTAAR1HTR2B
SCHEMBL244435 0.80 HTR2A (0.76) HTR2AHTR2CTAAR1HTR2BADRA1A
SCHEMBL10049625 0.80 HTR2A (0.48) HTR2AHTR2CTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250353808-A1 5-METHOXYMETHYL AND 5-HYDROXYMETHYL PHENETHYLAMINES 2A BIOSCIENCES, INC. 2025-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250353808-A1 5-METHOXYMETHYL AND 5-HYDROXYMETHYL PHENETHYLAMINES HTR5A, PNMT, HTR6 HTR2A 8/4885HTR2C 7/4885TAAR1 98/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.