Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.35 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31749310 | 0.89 | NAMPT (0.40) | CDK9DYRK1AGPR119SYKCHRM1 | |
| SCHEMBL24792702 | 0.77 | ALDH1A1 (0.39) | ESR2NR1H2 | |
| SCHEMBL20281771 | 0.77 | WNT3A (0.46) | ESR2GPR119NR1H2GRM5 | |
| SCHEMBL3986657 | 0.77 | ESR2 (0.45) | ESR2GPR119NR1H2 | |
| SCHEMBL17184835 | 0.76 | POLB (0.43) | CDK9ESR2GPR119NR1H2GRM5 | |
| SCHEMBL29197658 | 0.76 | ESR2 (0.55) | ESR2GPR119PIK3CDNR1H2 | |
| SCHEMBL25429308 | 0.76 | WDR5 (0.42) | ESR2GPR119NR1H2 | |
| SCHEMBL19458937 | 0.76 | GPR119 (0.41) | ESR2GPR119NR1H2 | |
| SCHEMBL22944325 | 0.76 | MAPK1 (0.44) | ESR2GPR119NR1H2 | |
| SCHEMBL31333649 | 0.75 | TBK1 (0.44) | CDK9ESR2GPR119NR1H2GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025264844-A1 | HETEROCYCLIC GPR52 MODULATORS AND METHODS OF USE THEREOF | LIEBER INSTITUTE, INC. (US) | 2025-12-26 | — | — | WO | disclosed |