Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | FABP1 | P07148 | 1/20 | 0.61 |
| ▸ | FABP6 | P51161 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.53 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15830494 | 0.86 | NOS2 (0.76) | NOS2MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL23408997 | 0.84 | NOS2 (0.72) | NOS2MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL16220824 | 0.84 | NOS2 (0.72) | NOS2MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL8419134 | 0.83 | MEN1 (0.72) | NOS2MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL10986892 | 0.83 | POLB (1.00) | NOS2MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL14818957 | 0.81 | NOS2 (0.69) | NOS2MEN1KMT2APOLBFABP1 | |
| SCHEMBL8422251 | 0.81 | MEN1 (0.68) | NOS2MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL15830499 | 0.80 | NOS2 (0.67) | NOS2MEN1KMT2APOLBHPGD | |
| SCHEMBL31240672 | 0.79 | NOS2 (0.66) | NOS2MEN1KMT2APOLBFABP1 | |
| SCHEMBL16041099 | 0.79 | NOS2 (0.66) | NOS2MEN1KMT2APOLBFABP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119529236-A | Epoxy resin composition, epoxy resin composition containing reinforcing fibers, prepreg, thermoplastic resin, and fiber-reinforced plastic | 日铁化学材料株式会社 | 2025-02-28 | — | — | CN | disclosed |
| WO-2023167049-A1 | EPOXY RESIN COMPOSITION, REINFORCING FIBER-CONTAINING EPOXY RESIN COMPOSITION, PREPREG, FIBER REINFORCED PLASTIC EMPLOYING SAME, AND THERMOPLASTIC EPOXY RESIN | 日鉄ケミカル＆マテリアル株式会社 | 2023-09-07 | — | — | WO | disclosed |
| WO-2021178488-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. (US) | 2021-09-10 | — | — | WO | disclosed |
| US-9669014-B2 | Small molecule inhibitors of superoxide dismutase expression | NORTHWESTERN UNIVERSITY (US) | 2017-06-06 | — | — | US | disclosed |
| US-9669014-B2 | Small molecule inhibitors of superoxide dismutase expression | NORTHWESTERN UNIVERSITY (US) | 2017-06-06 | — | — | US | disclosed |
| US-20160214969-A1 | SMALL MOLECULE INHIBITORS OF SUPEROXIDE DISMUTASE EXPRESSION | NORTHWESTERN UNIVERSITY (US) | 2016-07-28 | — | — | US | disclosed |
| US-20160214969-A1 | SMALL MOLECULE INHIBITORS OF SUPEROXIDE DISMUTASE EXPRESSION | NORTHWESTERN UNIVERSITY (US) | 2016-07-28 | — | — | US | disclosed |
| US-20150210679-A1 | SMALL MOLECULE INHIBITORS OF SUPEROXIDE DISMUTASE EXPRESSION | NORTHWESTERN UNIVERSITY (US) | 2015-07-30 | — | — | US | disclosed |
| US-20150210679-A1 | SMALL MOLECULE INHIBITORS OF SUPEROXIDE DISMUTASE EXPRESSION | NORTHWESTERN UNIVERSITY (US) | 2015-07-30 | — | — | US | disclosed |
| US-8623857-B2 | N-phenyl imidazole carboxamide inhibitors of 3-phosphoinositide-dependent protein kinase-1 | MERCK SHARP & DOHME CORP. (US) | 2014-01-07 | — | — | US | disclosed |
| US-20070142369-A1 | Combination of an H3 antagonist/inverse agonist and an appetite suppressant | SCHERING CORPORATION | 2007-06-21 | — | — | US | disclosed |
| US-20070072096-A1 | Negative curable dye-containing composition, color filter, and method of manufacturing the same | FUJI PHOTO FILM CO., LTD. | 2007-03-29 | — | — | US | disclosed |
| US-20050227290-A1 | Novel coordination complexes, and methods for preparing by combinatorial methods, assaying and using the same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-10-13 | — | — | US | disclosed |
| US-6806289-B1 | SUCH AS AMMINE (2-AMINO-3-PICOLINE) DICHLOROPLATINUM(II); EFFICIENCY AND SELECTIVITY FOR DESTROYING TRANSFORMED CELLS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-10-19 | — | — | US | disclosed |
| EP-1237849-A1 | ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | UNIVERSITY COLLEGE LONDON (GB) | 2002-09-11 | — | — | EP | disclosed |
| US-20020045679-A1 | Aqueous ink composition | HITACHI MAXELL, LTD. (JP) | 2002-04-18 | — | — | US | disclosed |
| WO-2001032604-A1 | ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | UNIVERSITY COLLEGE LONDON (GB) | 2001-05-10 | — | — | WO | disclosed |
| US-5972975-A | Substituted 2-aminopyridines as inhibitors of nitric oxide synthase | MERCK & CO., INC. (US) | 1999-10-26 | — | — | US | disclosed |
| WO-1996018616-A1 | SUBSTITUTED 2-AMINOPYRIDINES AS INHIBITORS OF NITRIC OXIDE SYNTHASE | MERCK & CO., INC. (US) | 1996-06-20 | — | — | WO | disclosed |
| EP-0000816-A1 | Substituted amino-pyridine derivatives, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1979-02-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160214969-A1 | SMALL MOLECULE INHIBITORS OF SUPEROXIDE DISMUTASE EXPRESSION | SOD1, SOD3, CAT | NOS2 986/4885MEN1 4869/4885KMT2A 3638/4885 |
| US-20070142369-A1 | Combination of an H3 antagonist/inverse agonist and an appetite suppressant | CNR2, GPR119, GLP1R | NOS2 2679/4885MEN1 991/4885KMT2A 193/4885 |
| US-20150210679-A1 | SMALL MOLECULE INHIBITORS OF SUPEROXIDE DISMUTASE EXPRESSION | SOD1, SOD3, CAT | NOS2 986/4885MEN1 4869/4885KMT2A 3638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.