Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Phenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 2/20 | 0.54 |
| ▸ | ESR1 known ✓ | P03372 | 10/20 | 0.50 |
| ▸ | ESR2 known ✓ | Q92731 | 10/20 | 0.50 |
| ▸ | EGFR known ✓ | P00533 | 1/20 | 0.47 |
| ▸ | PIK3CA known ✓ | P42336 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 4/20 | 0.92 |
| ▸ | CA2 | P00918 | 4/20 | 0.92 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.92 |
| ▸ | CA9 | Q16790 | 3/20 | 0.92 |
| ▸ | CA3 | P07451 | 3/20 | 0.92 |
| ▸ | CA4 | P22748 | 3/20 | 0.92 |
| ▸ | CA1 | P00915 | 2/20 | 0.92 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.92 |
| ▸ | GLA | P06280 | 1/20 | 0.92 |
| ▸ | MMP3 | P08254 | 1/20 | 0.59 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL28071734 | 1.00 | CA12 (0.92) | CA12CA2CA14CA9CA3 | |
| Phenol SCHEMBL27697610 | 1.00 | CA12 (0.92) | CA12CA2CA14CA9CA3 | |
| Phenol SCHEMBL27476284 | 1.00 | CA12 (0.92) | CA12CA2CA14CA9CA3 | |
| Phenol SCHEMBL28214421 | 1.00 | CA12 (0.92) | CA12CA2CA14CA9CA3 | |
| Phenol SCHEMBL16470227 | 1.00 | — | — | |
| Phenol SCHEMBL28824635 | 1.00 | CA12 (0.92) | CA12CA2CA14CA9CA3 | |
| Phenol SCHEMBL263258 | 1.00 | — | — | |
| Phenol SCHEMBL27678505 | 1.00 | CA12 (0.92) | CA12CA2CA14CA9CA3 | |
| Phenol SCHEMBL31338767 | 1.00 | CA12 (0.92) | CA12CA2CA14CA9CA3 | |
| Phenol SCHEMBL9820038 | 1.00 | CA12 (0.92) | CA12CA2CA14CA9CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119708316-A | Ethylene/alpha-olefin gradient copolymer and preparation method thereof | 中国科学院长春应用化学研究所 | 2025-03-28 | — | — | CN | claimed |
| EP-0001865-B1 | PROCESS FOR MAKING OBJECTS FROM MINERAL FILLERS BONDED WITH A THERMOSETTING RESIN | STAMICARBON B.V. (NL) | 1981-12-09 | — | — | EP | claimed |
| CN-119708316-A | Ethylene/alpha-olefin gradient copolymer and preparation method thereof | 中国科学院长春应用化学研究所 | 2025-03-28 | — | — | CN | disclosed |
| CN-119708316-A | Ethylene/alpha-olefin gradient copolymer and preparation method thereof | 中国科学院长春应用化学研究所 | 2025-03-28 | — | — | CN | disclosed |
| CN-118994450-A | Process for preparing ultra-high molecular weight narrow distribution poly alpha-olefin | 陕西煤业化工技术研究院有限责任公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-118994450-A | Process for preparing ultra-high molecular weight narrow distribution poly alpha-olefin | 陕西煤业化工技术研究院有限责任公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-118104796-A | Rice-free sushi and preparation method thereof | 无锡恩多寿司餐饮管理有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-114808539-A | Preparation method of fiber composite paper membrane for detecting aluminum ions | 东北林业大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-111469511-A | Composite high-strength washing powder packaging bag | 广东宝佳利绿印股份有限公司 | 2020-07-31 | — | — | CN | disclosed |
| CN-110183975-A | A kind of acrylic ester structural adhesive | 东莞市新懿电子材料技术有限公司 | 2019-08-30 | — | — | CN | disclosed |
| US-20100028798-A1 | TONER FOR ELECTROSTATIC LATENT IMAGE DEVELOPMENT AND IMAGE FORMING METHOD | KONICA MINOLTA HOLDINGS, INC. (JP) | 2010-02-04 | — | — | US | disclosed |
| CN-1930928-A | Partially etched dielectric film with conductive features | 3M INNOVATIVE PROPERTIES CO (US) | 2007-03-14 | — | — | CN | disclosed |
| EP-1045293-B1 | Toner, and process for producing a toner | CANON KK (JP) | 2007-01-10 | — | — | EP | disclosed |
| US-20060046175-A1 | Toner for electrostatic latent image development and image forming method | KONICA MINOLTA HOLDINGS, INC. (JP) | 2006-03-02 | — | — | US | disclosed |
| US-6326114-B1 | MIXTURE OF COLORING AGENT AND POLYESTER | CANON KABUSHIKI KAISHA (JP) | 2001-12-04 | — | — | US | disclosed |
| EP-1045293-A2 | Toner, and process for producing a toner | CANON KABUSHIKI KAISHA (JP) | 2000-10-18 | — | — | EP | disclosed |
| CN-1257528-A | Polyamide composition for the manufacture of articles by extrusion blow molding process and articles obtained | RHODIA PLASTICS ENGINEERING S (IT) | 2000-06-21 | — | — | CN | disclosed |
| US-5663275-A | POLYETHERIMIDES, HIGH MOLECULAR WEIGHT, ENGINEERING RESINS | GENERAL ELECTRIC COMPANY (US) | 1997-09-02 | — | — | US | disclosed |
| US-4202993-A | Method for making substantially anhydrous alkali metal bisphenol salts | GENERAL ELECTRIC COMPANY (US) | 1980-05-13 | — | — | US | disclosed |