Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 8/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL274925 | 0.88 | THRB (0.37) | TSHRTHRBACHECHRNB2CHRNB4 | |
| SCHEMBL15292049 | 0.86 | THRB (0.35) | TSHRTHRBACHECHRNB2CHRNB4 | |
| SCHEMBL889944 | 0.86 | TSHR (0.44) | TSHRTHRBACHECHRNB2CHRNB4 | |
| SCHEMBL24326826 | 0.84 | THRB (0.34) | TSHRTHRBACHEHRH3HRH4 | |
| SCHEMBL16328352 | 0.84 | THRB (0.34) | TSHRTHRBACHEHRH3HRH4 | |
| SCHEMBL24386246 | 0.84 | THRB (0.34) | TSHRTHRBACHEHRH3HRH4 | |
| SCHEMBL24326871 | 0.83 | THRB (0.33) | TSHRTHRBACHEHRH3HRH4 | |
| SCHEMBL21064764 | 0.83 | THRB (0.33) | TSHRTHRBACHEHRH3HRH4 | |
| SCHEMBL665126 | 0.82 | TSHR (0.52) | TSHRTHRBALDH1A1 | |
| SCHEMBL21579580 | 0.81 | TSHR (0.42) | TSHRTHRBACHEHRH3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2058318-B1 | PHOSPHATE ESTER COMPOUND, METAL SALT THEREOF, DENTAL MATERIAL, AND DENTAL COMPOSITION | MITSUI CHEMICALS INC (JP) | 2012-05-16 | — | — | EP | disclosed |
| US-20100024683-A1 | PHOSPHATE COMPOUND, METAL SALT THEREOF, DENTAL MATERIAL AND DENTAL COMPOSITION | MITSUI CHEMICALS, INC. (JP) | 2010-02-04 | — | — | US | disclosed |
| EP-2058318-A1 | PHOSPHATE ESTER COMPOUND, METAL SALT THEREOF, DENTAL MATERIAL, AND DENTAL COMPOSITION | Mitsui Chemicals, Inc. (JP) | 2009-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100024683-A1 | PHOSPHATE COMPOUND, METAL SALT THEREOF, DENTAL MATERIAL AND DENTAL COMPOSITION | CAD, PPIP5K2, SLC20A1 | TSHR 4810/4885THRB 4510/4885ACHE 3877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.