Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ARNT | P27540 | 2/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1752720 | 0.80 | GPR35 (0.40) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL5059457 | 0.80 | NPC1 (0.40) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL3183161 | 0.77 | TDP1 (0.37) | MEN1KMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL3290135 | 0.72 | — | — | |
| SCHEMBL7513494 | 0.71 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNAHIF1AVCAM1 | |
| SCHEMBL4614267 | 0.70 | NCEH1 (0.32) | MEN1KMT2APOLBTDP1 | |
| SCHEMBL5059455 | 0.70 | TDP1 (0.46) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL31589258 | 0.70 | ALDH1A1 (0.40) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL2333611 | 0.70 | TDP1 (0.41) | MEN1KMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL3203718 | 0.70 | TDP1 (0.41) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029013-A1 | Methods for Detecting Asymmetric Dimethylarginine in a Biological Sample | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-02-04 | — | — | US | disclosed |
| US-7611844-B2 | Methods for detecting asymmetric dimethylarginine in a biological sample | BOARD OF TRUSTEES OF THE LELAND STANFORD JR. UNIVERSITY (US) | 2009-11-03 | — | — | US | disclosed |
| US-20040214252-A1 | Methods for detecting asymmetric dimethylarginine in a biological sample | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-10-28 | — | — | US | disclosed |
| WO-2004046314-A2 | METHODS FOR DETECTING ASYMMETRIC DIMETHYLARGININE IN A BIOLOGICAL SAMPLE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2004-06-03 | — | — | WO | disclosed |
| US-4784962-A | Mixture of amino acid derivatives, process of producing the mixture and use of the mixture for quantitative determination of the amino acids | HEWLETT-PACKARD COMPANY (US) | 1988-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029013-A1 | Methods for Detecting Asymmetric Dimethylarginine in a Biological Sample | ADM2, PADI3, PADI4 | MEN1 1186/4885KMT2A 276/4885USP2 2246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.