Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.59 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.59 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.52 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2563667 | 1.00 | CA2 (0.71) | CA2MAPK1SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL458613 | 1.00 | CA2 (0.71) | CA2MAPK1SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL3865424 | 0.98 | CA2 (0.68) | CA2MAPK1SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL130285 | 0.93 | CA2 (0.61) | CA2MAPK1SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL130286 | 0.93 | CA2 (0.61) | CA2MAPK1SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL1857092 | 0.91 | GRIK1 (0.61) | CA2MAPK1SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL16970151 | 0.91 | GRIK1 (0.61) | CA2MAPK1SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL16969979 | 0.91 | GRIK1 (0.61) | CA2MAPK1SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL16970147 | 0.91 | GRIK1 (0.61) | CA2MAPK1SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL16970260 | 0.91 | GRIK1 (0.61) | CA2MAPK1SLC1A2SLC1A1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-8901119-B2 | Peptide deformylase inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 2) LIMITED (GB) | 2014-12-02 | — | — | US | disclosed |
| CN-103827665-A | Peptide deformylase inhibitors | GLAXOSMITHKLINE LLC | 2014-05-28 | — | — | CN | disclosed |
| US-20130345120-A1 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-12-26 | — | — | US | disclosed |
| US-7666659-B2 | Process for producing optically active 3-hydroxypropionic ester derivative | KANEKA CORPORATION (JP) | 2010-02-23 | — | — | US | disclosed |
| US-20100016627-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-HYDROXYPROPIONIC ESTER DERIVATIVE | KANEKA CORPORATION (JP) | 2010-01-21 | — | — | US | disclosed |
| WO-2009132832-A2 | METHOD FOR THE PRODUCTION OF 1,4-BENZOTHIEPIN-1,1-DIOXIDE DERIVATIVES | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-11-05 | — | — | WO | disclosed |
| US-7589216-B2 | Process for preparing N-hydroxyformamido-propyl pyrrolidin compounds and intermediates | NOVARTIS AG (CH) | 2009-09-15 | — | — | US | disclosed |
| US-7589216-B2 | Process for preparing N-hydroxyformamido-propyl pyrrolidin compounds and intermediates | NOVARTIS AG (CH) | 2009-09-15 | — | — | US | disclosed |
| US-7589216-B2 | Process for preparing N-hydroxyformamido-propyl pyrrolidin compounds and intermediates | NOVARTIS AG (CH) | 2009-09-15 | — | — | US | disclosed |
| CN-1759097-A | Chemical process for preparing intermediates for obtaining N-formyl hydroxylamines | NOVARTIS AG (CH) | 2006-04-12 | — | — | CN | disclosed |
| CN-1759097-A | Chemical process for preparing intermediates for obtaining N-formyl hydroxylamines | NOVARTIS AG (CH) | 2006-04-12 | — | — | CN | disclosed |
| EP-1599440-A2 | CHEMICAL PROCESS FOR THE PREPARATION OF INTERMEDIATES TO OBTAIN N-FORMYL HYDROXYLAMINE COMPOUNDS | Novartis AG (CH) | 2005-11-30 | — | — | EP | disclosed |
| EP-1599440-A2 | CHEMICAL PROCESS FOR THE PREPARATION OF INTERMEDIATES TO OBTAIN N-FORMYL HYDROXYLAMINE COMPOUNDS | Novartis AG (CH) | 2005-11-30 | — | — | EP | disclosed |
| US-20050261504-A1 | Process for preparing intermediates | NOVARTIS AG (CH) | 2005-11-24 | — | — | US | disclosed |
| CN-1684945-A | Process for preparing intermediates | NOVARTIS AG (CH) | 2005-10-19 | — | — | CN | disclosed |
| EP-1568679-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-HYDROXYPROPIONIC ESTER DERIVATIVE | KANEKA CORPORATION (JP) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004076053-A3 | CHEMICAL PROCESS FOR THE PREPARATION OF INTERMEDIATES TO OBTAIN N-FORMYL HYDROXYLAMINE COMPOUNDS | NOVARTIS AG (CH) | 2004-12-02 | — | — | WO | disclosed |
| WO-2004076053-A2 | CHEMICAL PROCESS FOR THE PREPARATION OF INTERMEDIATES TO OBTAIN N-FORMYL HYDROXYLAMINE COMPOUNDS | NOVARTIS AG (CH) | 2004-09-10 | — | — | WO | disclosed |
| WO-2004076053-A2 | CHEMICAL PROCESS FOR THE PREPARATION OF INTERMEDIATES TO OBTAIN N-FORMYL HYDROXYLAMINE COMPOUNDS | NOVARTIS AG (CH) | 2004-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016627-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-HYDROXYPROPIONIC ESTER DERIVATIVE | HPD, GRHPR, PAH | CA2 462/4885MAPK1 3054/4885SLC1A2 1740/4885 |
| US-20130345120-A1 | PEPTIDE DEFORMYLASE INHIBITORS | PDF, PEPD, VIP | CA2 4453/4885MAPK1 1754/4885SLC1A2 3898/4885 |
| US-20050261504-A1 | Process for preparing intermediates | DHPS, PDF, HPN | CA2 4666/4885MAPK1 4017/4885SLC1A2 4136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.