Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Tetradecane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 6/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | LAP3 | P28838 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetradecane SCHEMBL99243 | 0.84 | TP53 (0.68) | TP53SPHK1CA2CA1CYP2D6 | |
| Sulfuric Acid SCHEMBL19893760 | 0.82 | TP53 (0.60) | TP53SPHK1CA2CYP2D6GMNN | |
| Tetradecane SCHEMBL4030208 | 0.79 | TP53 (0.50) | TP53CA2CA1EPHX1CA9 | |
| Tetradecane SCHEMBL3227803 | 0.79 | TP53 (0.60) | TP53SPHK1CA2CA1EPHX1 | |
| Heptane SCHEMBL2057219 | 0.79 | TP53 (0.60) | TP53SPHK1CA2CA1EPHX1 | |
| Tetradecane SCHEMBL28202834 | 0.78 | TP53 (0.58) | TP53CA2CA1CA9 | |
| Tetradecane SCHEMBL7611438 | 0.78 | TP53 (0.58) | TP53CA2CA1CA9 | |
| Decane SCHEMBL13275986 | 0.78 | TSHR (0.57) | TP53CA2CA1LMNAEPHX1 | |
| Decane SCHEMBL13586006 | 0.78 | TSHR (0.57) | TP53CA2CA1LMNAEPHX1 | |
| Sulfuric Acid SCHEMBL1484174 | 0.78 | TSHR (0.57) | TP53CA2CA1LMNAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11576849-B2 | Antimicrobial personal cleansing compositions | CONOPCO, INC. (US) | 2023-02-14 | — | — | US | disclosed |
| US-20220226229-A1 | PERSONAL CLEANSING COMPOSITIONS | CONOPCO, INC., D/B/A UNILEVER | 2022-07-21 | — | — | US | disclosed |
| US-11364188-B2 | Antimicrobial personal cleansing compositions | CONOPCO, INC. (US) | 2022-06-21 | — | — | US | disclosed |
| EP-3986370-A1 | PERSONAL CLEANSING COMPOSITIONS | Unilever Global IP Limited (GB) | 2022-04-27 | — | — | EP | disclosed |
| EP-3600560-B1 | ANTIMICROBIAL PERSONAL CLEANSING COMPOSITIONS | UNILEVER IP HOLDINGS B V (NL) | 2021-10-13 | — | — | EP | disclosed |
| US-11129777-B2 | Microcapsules with improved deposition | FIRMENICH SA (CH) | 2021-09-28 | — | — | US | disclosed |
| US-20210220244-A1 | ANTIMICROBIAL PERSONAL CLEANSING COMPOSITIONS | CONOPCO, INC., D/B/A UNILEVER | 2021-07-22 | — | — | US | disclosed |
| US-20210196605-A1 | METHOD OF USE OF PERSONAL CLEANSING COMPOSITIONS | CONOPCO, INC., D/B/A UNILEVER | 2021-07-01 | — | — | US | disclosed |
| US-20210106513-A1 | ANTIMICROBIAL PERSONAL CLEANSING COMPOSITIONS | CONOPCO, INC., D/B/A UNILEVER | 2021-04-15 | — | — | US | disclosed |
| US-20210077377-A1 | PERSONAL CLEANSING COMPOSITIONS | CONOPCO INC DBA UNILEVER (US) | 2021-03-18 | — | — | US | disclosed |
| EP-2552387-A1 | SHAMPOO CONTAINING A DENDRITIC MACROMOLECULE AND A GEL NETWORK | Unilever PLC (GB) | 2013-02-06 | — | — | EP | disclosed |
| US-20130022567-A1 | HAIR CARE COMPOSITION COMPRISING ALKYL-MODIFIED SILOXANE | CONOPCO, INC., D/B/A UNILEVER | 2013-01-24 | — | — | US | disclosed |
| EP-2531169-A2 | SHAMPOO CONTAINING A GEL NETWORK | Unilever PLC, A Company Registered in England and Wales under Company no. 41424 (GB) | 2012-12-12 | — | — | EP | disclosed |
| WO-2012150260-A1 | HAIR CARE COMPOSITION COMPRISING HYDROPHOBICALLY-MODIFIED ANIONIC POLYMER AND A METHYLCELLULOSE | UNILEVER PLC (GB) | 2012-11-08 | — | — | WO | disclosed |
| WO-2012150259-A1 | COMPOSITION | UNILEVER PLC (GB) | 2012-11-08 | — | — | WO | disclosed |
| WO-2012004126-A2 | HAIR CARE COMPOSITION | UNILEVER PLC (GB) | 2012-01-12 | — | — | WO | disclosed |
| WO-2011120736-A1 | HAIR CARE COMPOSITION COMPRISING ALKYL -MODIFIED SILOXANE | UNILEVER PLC (GB) | 2011-10-06 | — | — | WO | disclosed |
| WO-2011117023-A1 | SHAMPOO CONTAINING A DENDRITIC MACROMOLECULE AND A GEL NETWORK | UNILEVER PLC (GB) | 2011-09-29 | — | — | WO | disclosed |
| US-20110212043-A1 | CONDITIONING SHAMPOO COMPOSITION COMPRISING AN AQUEOUS CONDITIONING GEL | CONOPCO, INC., D/B/A UNILEVER | 2011-09-01 | — | — | US | disclosed |
| WO-2011092083-A2 | COMPOSITION | UNILEVER PLC (GB) | 2011-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212043-A1 | CONDITIONING SHAMPOO COMPOSITION COMPRISING AN AQUEOUS CONDITIONING GEL | CXCL10, SGMS2, SGMS1 | TP53 3786/4885SPHK1 174/4885CA2 4268/4885 |
| US-20130022567-A1 | HAIR CARE COMPOSITION COMPRISING ALKYL-MODIFIED SILOXANE | SGMS1, SGMS2, SCNN1G | TP53 2134/4885SPHK1 643/4885CA2 1930/4885 |
| US-20220226229-A1 | PERSONAL CLEANSING COMPOSITIONS | C9, THOC2, PHOSPHO1 | TP53 4139/4885SPHK1 1079/4885CA2 1696/4885 |
| US-11364188-B2 | Antimicrobial personal cleansing compositions | CUTA, POLR1C, C9 | TP53 3592/4885SPHK1 892/4885CA2 730/4885 |
| US-20210220244-A1 | ANTIMICROBIAL PERSONAL CLEANSING COMPOSITIONS | CUTA, POLR1C, SCO2 | TP53 4373/4885SPHK1 1016/4885CA2 900/4885 |
| US-11576849-B2 | Antimicrobial personal cleansing compositions | NAMPT, ZDHHC7, ZDHHC2 | TP53 1710/4885SPHK1 519/4885CA2 3742/4885 |
| US-20210106513-A1 | ANTIMICROBIAL PERSONAL CLEANSING COMPOSITIONS | NAMPT, ZDHHC7, ZDHHC2 | TP53 1710/4885SPHK1 519/4885CA2 3742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.