Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8118405 | 1.00 | TDP1 (0.39) | TDP1CA1CA2CA9CA12 | |
| Hydrochloric Acid SCHEMBL719621 | 1.00 | TDP1 (0.39) | TDP1CA1CA2CA9CA12 | |
| Ethane SCHEMBL9064310 | 0.94 | TDP1 (0.35) | TDP1CA1CA2CA9CA12 | |
| Hydrochloric Acid SCHEMBL30626113 | 0.93 | TDP1 (0.39) | TDP1CA1CA2CA9CA12 | |
| Hydrochloric Acid SCHEMBL8007753 | 0.93 | TDP1 (0.39) | TDP1CA1CA2CA9CA12 | |
| Hydrochloric Acid SCHEMBL29009368 | 0.93 | TDP1 (0.39) | TDP1CA1CA2CA9CA12 | |
| Hydrochloric Acid SCHEMBL31456068 | 0.93 | TDP1 (0.39) | TDP1CA1CA2CA9CA12 | |
| Hydrochloric Acid SCHEMBL28072575 | 0.93 | TDP1 (0.39) | TDP1CA1CA2CA9CA12 | |
| Hydrochloric Acid SCHEMBL7777357 | 0.93 | TDP1 (0.39) | TDP1CA1CA2CA9CA12 | |
| Benzene SCHEMBL4445625 | 0.93 | TDP1 (0.44) | TDP1CA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894556-B | Synthesis method of beta-fluoroallylphosphine | 南通大学 | 2025-04-29 | — | — | CN | claimed |
| CN-119306732-A | Bioactive substance conjugate, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2025-01-14 | — | — | CN | claimed |
| CN-119241565-A | Aza [3.2.1] bridged ring substituted fluorescent dye and preparation method and application thereof | 北京大学 | 2025-01-03 | — | — | CN | claimed |
| CN-119219654-A | Bioactive substance conjugate, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-12-31 | — | — | CN | claimed |
| CN-118908930-A | Preparation method of 3-isochromone | 中国科学院大连化学物理研究所 | 2024-11-08 | — | — | CN | claimed |
| CN-118851992-A | Fluopicola strain method for synthesizing amide | 江苏海洋大学 | 2024-10-29 | — | — | CN | claimed |
| CN-118184968-A | Polymer acceptor material and preparation method and application thereof | 中国科学院苏州纳米技术与纳米仿生研究所 | 2024-06-14 | — | — | CN | claimed |
| WO-2024051354-A1 | BENZIMIDAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州沪云新药研发股份有限公司 | 2024-03-14 | — | — | WO | claimed |
| CN-115124535-B | Condensed ring indole compound and preparation method and application thereof | 中南民族大学 | 2024-02-27 | — | — | CN | claimed |
| CN-114213296-B | Naphthalene series liquid crystal monomer compound containing isothiocyanato and preparation method and application thereof | 中节能万润股份有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-112898555-A | Immobilized bimetallic catalyst and preparation method and application thereof | 万华化学集团股份有限公司 | 2021-06-04 | — | — | CN | claimed |
| CN-110511184-A | A kind of synthetic method of six and five and six fluorene kind derivatives | UNIV SHANDONG TECHNOLOGY | 2019-11-29 | — | — | CN | claimed |
| CN-110156657-A | A kind of synthetic method of 4- amino indole | 兰州大学 | 2019-08-23 | — | — | CN | claimed |
| CN-108467413-B | Cage compound, molecular capsule based on bowl alkene and the preparation method and application thereof | 北京师范大学 | 2019-07-12 | — | — | CN | claimed |
| CN-109988145-A | A kind of preparation method of sulfuric acid vinyl ester | 福建博鸿新能源科技有限公司 | 2019-07-09 | — | — | CN | claimed |
| CN-107266411-B | Synthesis method of 9, 10-benzophenanthrene compound | 百合花集团股份有限公司 | 2019-06-28 | — | — | CN | claimed |
| CN-109776589-A | The synthetic method of one group of boron nitrogen benzanthracene fused ring compound | 九江学院 | 2019-05-21 | — | — | CN | claimed |
| US-9650374-B2 | Photochromic tetrahydroindolizines | UMM AL-QURA UNIVERSITY (SA) | 2017-05-16 | — | — | US | claimed |
| WO-2016067069-A1 | NOVEL PHOTOCHROMIC TETRAHYDROINDOLIZINES | UMM AL-QURA UNIVERSITY (SA) | 2016-05-06 | — | — | WO | claimed |
| US-20160122338-A1 | NOVEL PHOTOCHROMIC TETRAHYDROINDOLIZINES | UMM AL-QURA UNIVERSITY (SA) | 2016-05-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160122338-A1 | NOVEL PHOTOCHROMIC TETRAHYDROINDOLIZINES | DHPS, TPH2, DHX15 | ACHE 2589/4885TDP1 740/4885CA1 2438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.