SCHEMBL3190409

SCHEMBL3190409

CCc1cc(CC)c(S(OS(=O)(=O)c2c(F)cccc2F)(c2ccccc2)c2ccccc2)c(CC)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.34
KMT2A Q03164 1/20 0.34
KAT6A Q92794 3/20 0.33
KEAP1 Q14145 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
PKM P14618 1/20 0.33
PSIP1 O75475 1/20 0.33
POLB P06746 2/20 0.32
F2 P00734 1/20 0.32
AKR1C3 P42330 1/20 0.32
METAP2 P50579 1/20 0.32
ESR1 P03372 1/20 0.32
HTR6 P50406 1/20 0.31
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3188845 0.88 CA1 (0.35) LMNAKAT6AHTR2AHTR2CPSIP1
SCHEMBL3193630 0.85 F2 (0.39) KMT2AHTR2AHTR2CPKMF2
SCHEMBL3200715 0.84 ALDH1A1 (0.32) LMNAKAT6APSIP1F2METAP2
SCHEMBL3194693 0.83 HTR2A (0.40) KMT2AHTR2AHTR2CPKMHTR6
SCHEMBL3197945 0.80 PPARG (0.36) LMNAKMT2AESR1ALDH1A1MAPT
SCHEMBL3201844 0.79 HSD11B1 (0.38) LMNAKMT2APOLBF2ALDH1A1
SCHEMBL3194867 0.78 KMT2A (0.38) LMNAKMT2AKAT6AKEAP1PKM
SCHEMBL3181566 0.77 KMT2A (0.41) LMNAKMT2AKAT6APKMMETAP2
SCHEMBL3194594 0.76 KAT6A (0.38) LMNAKMT2AKAT6APKMALDH1A1
SCHEMBL3197638 0.75 CYP3A4 (0.37) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206888-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2012-06-26 US disclosed
US-20100028800-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-04 US disclosed
EP-1953593-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2008-08-06 EP disclosed
US-7060414-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-06-13 US disclosed
US-20050158657-A1 Radiation-sensitive resin composition SUZUKI AKI (JP) 2005-07-21 US disclosed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US disclosed