SCHEMBL3197945

SCHEMBL3197945

CCc1cc(CC)c(S(OS(=O)(=O)c2c(C(F)(F)F)cc(C(F)(F)F)cc2C(F)(F)F)(c2ccccc2)c2ccccc2)c(CC)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.36
HSD11B1 P28845 3/20 0.34
TRPM8 Q7Z2W7 1/20 0.32
POLQ O75417 1/20 0.32
ALDH1A1 P00352 4/20 0.32
CYP3A4 P08684 3/20 0.32
CYP2D6 P10635 2/20 0.32
KDM4E B2RXH2 2/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
CYP2C9 P11712 2/20 0.32
CYP2C19 P33261 2/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32
TSHR P16473 1/20 0.32
HPGD P15428 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32
ESR1 P03372 1/20 0.32
RORC P51449 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3197638 0.88 CYP3A4 (0.37) PPARGHSD11B1TRPM8POLQALDH1A1
SCHEMBL3201844 0.86 HSD11B1 (0.38) PPARGHSD11B1ALDH1A1CYP3A4CYP2D6
SCHEMBL3200715 0.86 ALDH1A1 (0.32) PPARGHSD11B1TRPM8ALDH1A1KDM4E
SCHEMBL3194661 0.81 HSD11B1 (0.35) PPARGHSD11B1ALDH1A1CYP3A4CYP2D6
SCHEMBL3188845 0.81 CA1 (0.35) ALDH1A1KDM4ELMNAMAPTTP53
SCHEMBL3201689 0.80 CYP1A2 (0.44) PPARGHSD11B1ALDH1A1CYP3A4CYP2D6
SCHEMBL3204881 0.80 CYP3A4 (0.38) PPARGHSD11B1ALDH1A1CYP3A4CYP2D6
SCHEMBL3190409 0.80 LMNA (0.34) ALDH1A1LMNAMAPTESR1L3MBTL1
SCHEMBL3183484 0.77 ALDH1A1 (0.34) PPARGHSD11B1ALDH1A1CYP3A4KDM4E
SCHEMBL3193630 0.77 F2 (0.39) HSD11B1ALDH1A1KDM4EMAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206888-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2012-06-26 US disclosed
US-20100028800-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-04 US disclosed
EP-1953593-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2008-08-06 EP disclosed
US-7060414-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-06-13 US disclosed
US-20050158657-A1 Radiation-sensitive resin composition SUZUKI AKI (JP) 2005-07-21 US disclosed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US disclosed