SCHEMBL3200715

SCHEMBL3200715

CCc1cc(CC)c(S(OS(=O)(=O)c2c(C(F)(F)F)c(C(F)(F)F)c(C(F)(F)F)c(C(F)(F)F)c2C(F)(F)F)(c2ccccc2)c2ccccc2)c(CC)c1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.32
PSIP1 O75475 1/20 0.32
HSD11B1 P28845 3/20 0.32
PPARG P37231 1/20 0.32
F2 P00734 2/20 0.31
TRPM8 Q7Z2W7 1/20 0.31
RORC P51449 3/20 0.31
METAP2 P50579 1/20 0.31
MAPT P10636 2/20 0.31
LOXL2 Q9Y4K0 2/20 0.31
NPC1 O15118 1/20 0.31
LMNA P02545 1/20 0.31
MAPK1 P28482 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
NR1I2 O75469 2/20 0.30
NR1H3 Q13133 2/20 0.30
KAT6A Q92794 1/20 0.30
RORA P35398 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3197945 0.86 PPARG (0.36) ALDH1A1HSD11B1PPARGTRPM8RORC
SCHEMBL3201844 0.85 HSD11B1 (0.38) ALDH1A1HSD11B1PPARGF2MAPT
SCHEMBL3188845 0.85 CA1 (0.35) ALDH1A1PSIP1F2METAP2MAPT
SCHEMBL3190409 0.84 LMNA (0.34) ALDH1A1PSIP1F2METAP2MAPT
SCHEMBL3193630 0.81 F2 (0.39) ALDH1A1HSD11B1F2METAP2MAPT
SCHEMBL3197638 0.81 CYP3A4 (0.37) ALDH1A1HSD11B1PPARGTRPM8NR1I2
SCHEMBL3199775 0.78 CYP1A2 (0.42) ALDH1A1METAP2MAPTLMNAMAPK1
SCHEMBL3193036 0.78 HSD11B1 (0.33) ALDH1A1HSD11B1MAPTLMNASMN1; SMN2
SCHEMBL3194693 0.77 HTR2A (0.40) ALDH1A1MAPK1SMN1; SMN2
SCHEMBL3200054 0.76 FFAR4 (0.35) ALDH1A1HSD11B1MAPTLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206888-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2012-06-26 US disclosed
US-20100028800-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-04 US disclosed
EP-1953593-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2008-08-06 EP disclosed
US-7060414-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-06-13 US disclosed
US-20050158657-A1 Radiation-sensitive resin composition SUZUKI AKI (JP) 2005-07-21 US disclosed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US disclosed