SCHEMBL3201844

SCHEMBL3201844

CCc1cc(CC)c(S(OS(=O)(=O)c2ccc(C(F)(F)F)cc2)(c2ccccc2)c2ccccc2)c(CC)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 4/20 0.38
CYP19A1 P11511 1/20 0.37
CYP3A4 P08684 3/20 0.37
CYP2C19 P33261 3/20 0.37
CYP1A2 P05177 2/20 0.37
CYP2D6 P10635 2/20 0.37
CYP2C9 P11712 2/20 0.37
POLB P06746 2/20 0.37
MAPT P10636 2/20 0.37
LMNA P02545 1/20 0.37
GAA P10253 1/20 0.37
MAPK1 P28482 1/20 0.37
HTT P42858 1/20 0.37
TP53 P04637 1/20 0.37
TSHR P16473 1/20 0.37
AR P10275 1/20 0.37
BCHE P06276 1/20 0.36
ACHE P22303 1/20 0.36
PTGS2 P35354 1/20 0.36
CA1 P00915 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3193630 0.86 F2 (0.39) HSD11B1CYP19A1MAPTMAPK1TP53
SCHEMBL3201041 0.86 ALDH1A1 (0.43) HSD11B1CYP19A1CYP3A4CYP2C19CYP1A2
SCHEMBL3197945 0.86 PPARG (0.36) HSD11B1CYP3A4CYP2C19CYP1A2CYP2D6
SCHEMBL3197638 0.85 CYP3A4 (0.37) HSD11B1CYP3A4CYP2C19CYP1A2CYP2D6
SCHEMBL3200715 0.85 ALDH1A1 (0.32) HSD11B1MAPTLMNAMAPK1PTGS2
SCHEMBL3139775 0.80 HSD11B1 (0.45) HSD11B1POLBMAPTLMNAHTT
SCHEMBL3132687 0.80 HSD11B1 (0.45) HSD11B1POLBMAPTLMNAHTT
SCHEMBL503702 0.80 HSD11B1 (0.45) HSD11B1POLBMAPTLMNAHTT
SCHEMBL3188845 0.80 CA1 (0.35) POLBMAPTLMNAMAPK1TP53
SCHEMBL3190409 0.79 LMNA (0.34) POLBMAPTLMNAMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050158657-A1 Radiation-sensitive resin composition SUZUKI AKI (JP) 2005-07-21 US claimed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US claimed
US-20020090569-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2002-07-11 US claimed
US-8206888-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2012-06-26 US disclosed
US-20100028800-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-04 US disclosed
EP-1953593-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2008-08-06 EP disclosed
US-7060414-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-06-13 US disclosed
US-20050158657-A1 Radiation-sensitive resin composition SUZUKI AKI (JP) 2005-07-21 US disclosed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US disclosed