Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.42 |
| ▸ | TYR | P14679 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18220538 | 0.84 | CTSL (0.38) | HMGCRTYRMAPTALOX5MEN1 | |
| SCHEMBL7761403 | 0.76 | PRKCI (0.47) | HMGCRTYRMAPTALOX5MEN1 | |
| SCHEMBL1249490 | 0.76 | MPL (0.43) | ALOX5CNR1CNR2 | |
| SCHEMBL20111275 | 0.75 | HMGCR (0.41) | HMGCRTYRMAPTALOX5MEN1 | |
| SCHEMBL17487399 | 0.74 | NOS1 (0.33) | CTSLCTSSCTSK | |
| SCHEMBL17487398 | 0.74 | NOS1 (0.33) | CTSLCTSSCTSK | |
| SCHEMBL5510375 | 0.74 | ESR1 (0.42) | MAPTMEN1TP53CYP3A4ALOX15 | |
| SCHEMBL3179945 | 0.73 | MAPT (0.37) | MAPTMEN1TP53TSHRHTT | |
| SCHEMBL21299210 | 0.72 | PRKCI (0.38) | HMGCRTYRMAPTALOX5MEN1 | |
| SCHEMBL3179887 | 0.72 | ALOX5 (0.40) | MAPTALOX5MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1852411-B1 | TRIFLUORONAPHTHALENE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE COMPOUND | DAINIPPON INK & CHEMICALS (JP) | 2010-11-10 | — | — | EP | disclosed |
| US-7662442-B2 | Trifluoronaphthalene derivative and liquid crystal composition containing the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2010-02-16 | — | — | US | disclosed |
| US-20090121186-A1 | TRIFLUORONAPHTHALENE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2009-05-14 | — | — | US | disclosed |
| EP-1852411-A1 | TRIFLUORONAPHTHALENE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE COMPOUND | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2007-11-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090121186-A1 | TRIFLUORONAPHTHALENE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | TCF4, DVL1, TCF12 | HMGCR 2909/4885TYR 1799/4885MAPT 507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.