SCHEMBL3190799

SCHEMBL3190799

C(=NC(N=Cc1ccccc1)c1ccccc1)c1ccccc1.Cn1c(C=O)cc2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
GRIN2D O15399 1/20 0.42
GRIN3B O60391 1/20 0.42
GRIN1 Q05586 1/20 0.42
GRIN2A Q12879 1/20 0.42
GRIN2B Q13224 1/20 0.42
GRIN2C Q14957 1/20 0.42
GRIN3A Q8TCU5 1/20 0.42
MCL1 Q07820 1/20 0.38
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ALB P02768 1/20 0.35
DAO P14920 1/20 0.35
ABCC2 Q92887 1/20 0.33
SLC9A1 P19634 1/20 0.33
PHGDH O43175 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29894136 0.79 GRIN2D (0.51) KMT2AMEN1GRIN2DGRIN3BGRIN1
SCHEMBL342762 0.79 GRIN2D (0.51) KMT2AMEN1GRIN2DGRIN3BGRIN1
SCHEMBL3190182 0.76 TRIM24 (0.56) KMT2AMEN1NPC1RAB9AALDH1A1
Benzaldehyde SCHEMBL3185067 0.74 ALDH1A1 (0.54) KMT2AMEN1GRIN2DGRIN3BGRIN1
2-Naphthaldehyde SCHEMBL3184404 0.73 RELA (0.45) KMT2AMEN1RAB9AGRIN2DGRIN3B
SCHEMBL3187211 0.72 ALDH1A1 (0.62) KMT2AMEN1NPC1RAB9AALDH1A1
SCHEMBL151524 0.72 LMNA (0.50) KMT2AMEN1GRIN2DGRIN3BGRIN1
SCHEMBL14163512 0.72 LMNA (0.50) KMT2AMEN1GRIN2DGRIN3BGRIN1
SCHEMBL3186046 0.72 RRM1 (0.38) KMT2AMEN1NPC1RAB9AALDH1A1
SCHEMBL3194567 0.70 ERN1 (0.36) MCL1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7671138-B2 Polymers functionized with hydrobenzamides BRIDGESTONE CORPORATION (JP) 2010-03-02 US claimed
US-20070276098-A1 Polymers functionalized with hydrobenzamide BRIDGESTONE CORPORATION 2007-11-29 US claimed
US-20070276122-A1 Polymers functionalized with hydrobenzamides BRIDGESTONE CORPORATION 2007-11-29 US claimed
US-7671138-B2 Polymers functionized with hydrobenzamides BRIDGESTONE CORPORATION (JP) 2010-03-02 US disclosed
US-20070276122-A1 Polymers functionalized with hydrobenzamides BRIDGESTONE CORPORATION 2007-11-29 US disclosed
US-20070276098-A1 Polymers functionalized with hydrobenzamide BRIDGESTONE CORPORATION 2007-11-29 US disclosed