Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16600332 | 1.00 | AKR1B1 (0.57) | AKR1B1LMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL1658629 | 1.00 | AKR1B1 (0.57) | AKR1B1LMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL25916469 | 1.00 | AKR1B1 (0.57) | AKR1B1LMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL447075 | 1.00 | AKR1B1 (0.57) | AKR1B1LMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL5319919 | 1.00 | AKR1B1 (0.57) | AKR1B1LMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL1747065 | 1.00 | AKR1B1 (0.57) | AKR1B1LMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL28179278 | 0.97 | AKR1B1 (0.55) | AKR1B1LMNAL3MBTL1TDP1PDE4A | |
| Acetic Acid SCHEMBL13571451 | 0.91 | AKR1B1 (0.48) | AKR1B1LMNAL3MBTL1PDE4A | |
| Phosphoric Acid SCHEMBL5790105 | 0.91 | AKR1B1 (0.48) | AKR1B1LMNAL3MBTL1 | |
| Acetone SCHEMBL8217200 | 0.91 | AKR1B1 (0.48) | AKR1B1LMNAL3MBTL1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 468 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230193336-A1 | ENASIDENIB GLYCOSIDES AND METHODS OF TREATING DISEASES ASSOCIATED WITH ISOCITRATE DEHYDROGENASE (IDH) DYSFUNCTION | DOUBLERAINBOW BIOSCIENCES INC. | 2023-06-22 | — | — | US | claimed |
| US-20230192748-A1 | Etoposide Glycosides, Methods Of Making, And Uses Thereof As An Anti-Cancer Drug | DOUBLERAINBOW BIOSCIENCES INC. | 2023-06-22 | — | — | US | claimed |
| US-20230124589-A1 | Ivacaftor Glycosides, Methods Of Making, And Uses Thereof In Treating Cystic Fibrosis | DOUBLERAINBOW BIOSCIENCES INC. | 2023-04-20 | — | — | US | claimed |
| CN-115279915-A | Etoposide glycoside, preparation method thereof and application thereof as anticancer drug | 德瑞生物医药股份有限公司 | 2022-11-01 | — | — | CN | claimed |
| US-10610539-B2 | Cardiac glycoside analogs and their use in methods for inhibition of viral infection | THE JOHN HOPKINS UNIVERSITY (US) | 2020-04-07 | — | — | US | claimed |
| US-10188511-B2 | Bioprosthetic tissue with reduced calcification | EDWARDS LIFESCIENCES CORPORATION (US) | 2019-01-29 | — | — | US | claimed |
| US-20160235528-A1 | BIOPROSTHETIC TISSUE WITH REDUCED CALCIFICATION | EDWARDS LIFESCIENCES CORPORATION | 2016-08-18 | — | — | US | claimed |
| EP-1885379-B1 | COMPOUNDS AND METHODS FOR TREATING SEIZURE AND PAROXYSMAL DISORDERS | WISCONSIN ALUMNI RES FOUND (US) | 2016-07-20 | — | — | EP | claimed |
| US-20160143934-A1 | CARDIAC GLYCOSIDE ANALOGS AND THEIR USE IN METHODS FOR INHIBITION OF VIRAL INFECTION | THE JOHNS HOPKINS UNIVERSITY | 2016-05-26 | — | — | US | claimed |
| US-9296774-B2 | Halogenated dideoxy sugar derivates, preparation method and application thereof | SUZHOU HARMONY BIOTECHNOLOGY CO., LTD. (CN) | 2016-03-29 | — | — | US | claimed |
| US-20060217303-A1 | Compounds and Methods for Treating Seizure Disorders | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2006-09-28 | — | — | US | claimed |
| US-20060205649-A1 | Metabolic-based methods for modulating gene expression | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2006-09-14 | — | — | US | claimed |
| WO-2006088849-A2 | METABOLIC-BASED METHODS FOR MODULATING GENE EXPRESSION | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2006-08-24 | — | — | WO | claimed |
| US-20060088517-A1 | Compounds and methods for treating seizure disorders | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2006-04-27 | — | — | US | claimed |
| US-20060041109-A1 | Neoglycorandomization and digitoxin analogs | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2006-02-23 | — | — | US | claimed |
| WO-2006002381-A1 | NEOGLYCORANDOMIZATION AND DIGITOXIN ANALOGS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2006-01-05 | — | — | WO | claimed |
| WO-2006002121-A2 | COMPOUNDS AND METHODS FOR TREATING SEIZURE AND PAROXYSMAL DISORDERS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2006-01-05 | — | — | WO | claimed |
| US-6218435-B1 | Reduction of hair growth | HENRY JAMES (US) | 2001-04-17 | — | — | US | claimed |
| EP-0863741-A2 | REDUCTION OF HAIR GROWTH | HANDELMAN, Joseph H. (US) | 1998-09-16 | — | — | EP | claimed |
| WO-1997019673-A2 | REDUCTION OF HAIR GROWTH | HANDELMAN, JOSEPH, H. (US) | 1997-06-05 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10610539-B2 | Cardiac glycoside analogs and their use in methods for inhibition of viral infection | ATP1A3, ATP1A2, ATP1B3 | AKR1B1 381/4885LMNA 2288/4885L3MBTL1 4696/4885 |
| US-20230124589-A1 | Ivacaftor Glycosides, Methods Of Making, And Uses Thereof In Treating Cystic Fibrosis | UGGT1, UGDH, GALE | AKR1B1 372/4885LMNA 3103/4885L3MBTL1 1359/4885 |
| US-20060041109-A1 | Neoglycorandomization and digitoxin analogs | CANX, DERA, GALE | AKR1B1 970/4885LMNA 4050/4885L3MBTL1 3460/4885 |
| US-20230193336-A1 | ENASIDENIB GLYCOSIDES AND METHODS OF TREATING DISEASES ASSOCIATED WITH ISOCITRATE DEHYDROGENASE (IDH) DYSFUNCTION | UGDH, IDH1, G6PD | AKR1B1 244/4885LMNA 3336/4885L3MBTL1 1574/4885 |
| US-20230192748-A1 | Etoposide Glycosides, Methods Of Making, And Uses Thereof As An Anti-Cancer Drug | GALE, UGGT1, DERA | AKR1B1 550/4885LMNA 2057/4885L3MBTL1 1063/4885 |
| US-20160143934-A1 | CARDIAC GLYCOSIDE ANALOGS AND THEIR USE IN METHODS FOR INHIBITION OF VIRAL INFECTION | ATP1A3, ATP1A2, ATP1B3 | AKR1B1 381/4885LMNA 2288/4885L3MBTL1 4696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.