Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 5/20 | 0.55 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 8/20 | 0.46 |
| ▸ | ITK | Q08881 | 6/20 | 0.46 |
| ▸ | BTK | Q06187 | 4/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3197660 | 0.91 | TGM2 (0.55) | TGM2MAP2K7EGFRITKBTK | |
| SCHEMBL3197656 | 0.90 | TGM2 (0.56) | TGM2MAP2K7EGFRITKBTK | |
| SCHEMBL3193313 | 0.81 | TGM2 (0.63) | TGM2MAP2K7 | |
| SCHEMBL3200141 | 0.80 | TGM2 (0.46) | TGM2MAP2K7EGFRBTK | |
| SCHEMBL1383792 | 0.80 | TGM2 (0.66) | TGM2EGFRITKMMP1MMP2 | |
| SCHEMBL31069810 | 0.80 | TGM2 (0.66) | TGM2EGFRITKMMP1MMP2 | |
| SCHEMBL10946691 | 0.80 | TGM2 (0.59) | TGM2MAP2K7EGFRITKBTK | |
| SCHEMBL22732031 | 0.79 | TGM2 (0.74) | TGM2MAP2K7EGFRITKBTK | |
| SCHEMBL4103284 | 0.79 | TGM2 (0.76) | TGM2MAP2K7EGFRITKBTK | |
| SCHEMBL3192042 | 0.78 | TDP1 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100024683-A1 | PHOSPHATE COMPOUND, METAL SALT THEREOF, DENTAL MATERIAL AND DENTAL COMPOSITION | MITSUI CHEMICALS, INC. (JP) | 2010-02-04 | — | — | US | disclosed |
| EP-2058318-A1 | PHOSPHATE ESTER COMPOUND, METAL SALT THEREOF, DENTAL MATERIAL, AND DENTAL COMPOSITION | Mitsui Chemicals, Inc. (JP) | 2009-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100024683-A1 | PHOSPHATE COMPOUND, METAL SALT THEREOF, DENTAL MATERIAL AND DENTAL COMPOSITION | CAD, PPIP5K2, SLC20A1 | TGM2 4191/4885MAP2K7 837/4885EGFR 4663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.