SCHEMBL3195484

SCHEMBL3195484

CCCCc1ccc(-c2c(Nc3c(C)cccc3CC)ccc(-c3ccc(-c4ccc(Nc5c(C)cccc5CC)cc4)cc3)c2-c2ccc(CCCC)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.38
MMP2 P08253 1/20 0.35
MMP3 P08254 1/20 0.35
RARB P10826 2/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
NPSR1 Q6W5P4 3/20 0.33
POLB P06746 2/20 0.32
ATM Q13315 1/20 0.32
UNG P13051 3/20 0.32
HPGD P15428 3/20 0.32
ALDH1A1 P00352 2/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
CASP3 P42574 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3782358 0.85 RARB (0.39) PTGS2RARBMEN1KMT2ANPSR1
SCHEMBL3776574 0.83 MMP2 (0.38) MMP2MMP3RARBMEN1KMT2A
SCHEMBL3195478 0.83 RARB (0.38) PTGS2MMP2MMP3RARBMEN1
SCHEMBL919587 0.82 MEN1 (0.39) RARBMEN1KMT2ANPSR1POLB
SCHEMBL1726976 0.79 TRPV1 (0.41) RARBMEN1KMT2ANPSR1HPGD
SCHEMBL3990796 0.78 TRPV1 (0.42) RARBMEN1KMT2ANPSR1HPGD
SCHEMBL17549426 0.76 PTGS2 (0.51) PTGS2MEN1KMT2APOLBALDH1A1
SCHEMBL30966312 0.76 PTGS2 (0.51) PTGS2MEN1KMT2APOLBALDH1A1
SCHEMBL20011643 0.74 ALDH1A1 (0.50) MEN1KMT2ANPSR1POLBATM
SCHEMBL27957227 0.74 HSD11B1 (0.40) MEN1KMT2ANPSR1HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7670736-B2 Photoconductors XEROX CORPORATION (US) 2010-03-02 US claimed
US-7662525-B2 Anticurl backside coating (ACBC) photoconductors XEROX CORPORATION (US) 2010-02-16 US claimed