Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | ELANE | P08246 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | GLI1 | P08151 | 1/20 | 0.35 |
| ▸ | GLI2 | P10070 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7764517 | 0.98 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2RAB9AHPGDHTT | |
| Hydrochloric Acid SCHEMBL1683544 | 0.90 | ALDH1A1 (0.40) | ALDH1A1RAB9APTGS2KDM4ECYP3A4 | |
| SCHEMBL2743760 | 0.88 | TSHR (0.41) | ALDH1A1RAB9APTGS2KDM4ECYP3A4 | |
| Fluoride Ion SCHEMBL29161106 | 0.87 | TSHR (0.40) | ALDH1A1RAB9APTGS2KDM4ECYP3A4 | |
| Bromide SCHEMBL28360563 | 0.87 | TSHR (0.40) | ALDH1A1RAB9APTGS2KDM4ECYP3A4 | |
| Iodide SCHEMBL29161127 | 0.87 | TSHR (0.40) | ALDH1A1SMN1; SMN2RAB9AHPGDPTGS2 | |
| Hydrochloric Acid SCHEMBL7605623 | 0.84 | THRB (0.37) | — | |
| Ethyl Chloride SCHEMBL5032976 | 0.84 | TSHR (0.37) | ALDH1A1SMN1; SMN2RAB9AHPGDPTGS2 | |
| Hydrochloric Acid SCHEMBL28406302 | 0.83 | TGM2 (0.36) | ALDH1A1RAB9AHPGDNPSR1L3MBTL1 | |
| SCHEMBL6562054 | 0.83 | THRB (0.38) | MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118873440-A | Composition with conditioning and puffing effects and application of composition in shampoo products | 广州凡岛网络科技有限公司 | 2024-11-01 | — | — | CN | claimed |
| US-20100029853-A1 | Controlled architecture copolymers prepared from vinyl phosphonate monomers | Rhodia Receherches et Technologies (FR) | 2010-02-04 | — | — | US | claimed |
| US-20090306297-A1 | PROCESS FOR PREPARING A COPOLYMER WITH CONTROLLED ARCHITECTURE, OF TELOMER OR BLOCK COPOLYMER TYPE, OBTAINED FROM VINYL PHOSPHONATE MONOMERS, BY IODINE TRANSFER POLYMERIZATION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-12-10 | — | — | US | claimed |
| CN-114080271-B | Method of preparing a personal care composition comprising microcapsules | 宝洁公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-114601744-B | Delivery of surfactant soluble anti-dandruff agents | 宝洁公司 | 2024-12-20 | — | — | CN | disclosed |
| CN-114981016-B | Bottle suitable for storing liquid compositions having an aesthetic design suspended therein | 宝洁公司 | 2024-11-19 | — | — | CN | disclosed |
| CN-118873440-A | Composition with conditioning and puffing effects and application of composition in shampoo products | 广州凡岛网络科技有限公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-118265516-A | Sulfate-free personal cleansing compositions with effective preservation | 宝洁公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-114632026-B | Compositions comprising scalp health agents with increased deposition | 宝洁公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-118139608-A | Sulfate-free personal cleansing compositions comprising low inorganic salt content and hydroxamic acid or hydroxamic acid derivatives | 宝洁公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-117999063-A | Sulfate-free conditioning shampoo compositions containing cationic polymer and inorganic salt | 宝洁公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-111278511-B | Compact shampoo compositions | 宝洁公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-111194207-B | Compact shampoo compositions comprising sulfate-free surfactants | 宝洁公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-109715131-B | Low viscosity hair care compositions | 宝洁公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-108697596-B | Personal care compositions with zinc-containing layered materials | 宝洁公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-107072934-B | Personal care compositions and methods of preparation | 宝洁公司 | 2021-01-22 | — | — | CN | disclosed |
| US-20100029853-A1 | Controlled architecture copolymers prepared from vinyl phosphonate monomers | Rhodia Receherches et Technologies (FR) | 2010-02-04 | — | — | US | disclosed |
| US-20090306297-A1 | PROCESS FOR PREPARING A COPOLYMER WITH CONTROLLED ARCHITECTURE, OF TELOMER OR BLOCK COPOLYMER TYPE, OBTAINED FROM VINYL PHOSPHONATE MONOMERS, BY IODINE TRANSFER POLYMERIZATION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-12-10 | — | — | US | disclosed |
| US-7579400-B2 | Particles having an organized internal structure which are dispersed in an aqueous phase, the preparation thereof and use of same | RHODIA CHIMIE (FR) | 2009-08-25 | — | — | US | disclosed |
| US-20050245672-A1 | Particles having an organized internal structure which are dispersed in an aqueous phase, the preparation thereof and use of same | RHODIA CHIMIE (FR) | 2005-11-03 | — | — | US | disclosed |