SCHEMBL3197749

SCHEMBL3197749

Cc1cc2c(cc1C)C(=O)C=CC2=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.48
CDC25B P30305 2/20 0.46
IDO1 P14902 2/20 0.43
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
AKT1 P31749 1/20 0.43
SNCA P37840 1/20 0.43
MAP2K1 Q02750 1/20 0.43
PIN1 Q13526 1/20 0.43
EHMT2 Q96KQ7 1/20 0.43
NSD1 Q96L73 1/20 0.43
EHMT1 Q9H9B1 1/20 0.43
S100A4 P26447 1/20 0.39
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38
GRIN1 Q05586 1/20 0.38
GRIN2A Q12879 1/20 0.38
GRIN2B Q13224 1/20 0.38
GRIN2C Q14957 1/20 0.38
GRIN3A Q8TCU5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27554383 0.84 S100A4 (0.39) PIM1CDC25BIDO1MAOAMAOB
SCHEMBL18666618 0.82 GRIN2D (0.43) PIM1CDC25BIDO1MAOAMAOB
SCHEMBL3420118 0.73 NQO1 (0.50) CDC25BMAOAMAOBGRIN2DGRIN3B
SCHEMBL169650 0.73 MAOA (0.54) PIM1CDC25BIDO1MAOAMAOB
SCHEMBL9171554 0.71 PIM1 (0.46) PIM1CDC25BIDO1MAOAMAOB
SCHEMBL1134711 0.71 CYP3A4 (0.41) MAOAGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL9751019 0.71 NQO1 (0.54) MAOAMAOBS100A4GRIN2DGRIN3B
SCHEMBL10421261 0.71 NQO1 (0.48) CDC25BMAOAMAOBGRIN2DGRIN3B
SCHEMBL9627487 0.71 MAPT (0.56) CDC25BIDO1MAOAMAOBSNCA
SCHEMBL30002691 0.71 MAPT (0.56) CDC25BIDO1MAOAMAOBSNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117024408-A 1,2, 3-triaryl substituted benzo [ f ] isoindole-4, 9-dione compound and preparation method and application thereof 湘潭大学 2023-11-10 CN claimed
CN-115141204-B Naphthalene [1,2-b ] furan-4, 5-dione derivative, preparation and application thereof 浙江大学 2024-01-02 CN disclosed
CN-117024408-A 1,2, 3-triaryl substituted benzo [ f ] isoindole-4, 9-dione compound and preparation method and application thereof 湘潭大学 2023-11-10 CN disclosed
CN-109553756-B Method for producing phosphorus-containing epoxy resin 日铁化学材料株式会社 2023-09-29 CN disclosed
US-11613509-B2 Radical polymerization control agent and radical polymerization control method KAWASAKI KASEI CHEMICALS LTD. (JP) 2023-03-28 US disclosed
CN-115141204-A Naphthalene [1,2-b ] furan-4,5-diketone derivative and preparation and application thereof 浙江大学 2022-10-04 CN disclosed
CN-110891980-B Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2022-09-30 CN disclosed
US-20210122692-A1 RADICAL POLYMERIZATION CONTROL AGENT AND RADICAL POLYMERIZATION CONTROL METHOD KAWASAKI KASEI CHEMICALS LTD. (JP) 2021-04-29 US disclosed
CN-110891980-A Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2020-03-17 CN disclosed
CN-109553756-A The manufacturing method of phosphorous epoxy resin 日铁化学材料株式会社 2019-04-02 CN disclosed
EP-2135671-A2 Catalyst and method for producing carboxylic acid and/or carboxylic anhydride in the presence of the catalyst Mitsubishi Gas Chemical Company, Inc. (JP) 2009-12-23 EP disclosed
CN-101263622-A Non-aqueous electrolyte for primary battery and non-aqueous electrolyte primary battery using the same MITSUBISHI CHEM CORP (JP) 2008-09-10 CN disclosed
EP-1933404-A1 NON-AQUEOUS ELECTROLYTE FOR PRIMARY BATTERY, AND NON-AQUEOUS ELECTROLYTE PRIMARY BATTERY USING THE SAME Mitsubishi Chemical Corporation (JP) 2008-06-18 EP disclosed
US-5338863-A Catalytic sulfiding CIBA-GEIGY CORPORATION (US) 1994-08-16 US disclosed
US-5206390-A Intermediates for tetrathiotetracenes CIBA-GEIGY CORPORATION (US) 1993-04-27 US disclosed
EP-0195743-A2 Enol ethers, process for their preparation, alpha-pyrones, process for their preparation and use of the alpha-pyrones CIBA-GEIGY AG (CH) 1986-09-24 EP disclosed
US-4424361-A Process for preparing polycyclic triazoles used to inhibit allergic responses BEECHAM GROUP LIMITED (GB) 1984-01-03 US disclosed
US-4419439-A ALKOXYNAPHTHOL DEVELOPER FUJI PHOTO FILM CO., LTD. (JP) 1983-12-06 US disclosed
EP-0033214-A2 Process for preparing therapeutically active triazoles BEECHAM GROUP PLC (GB) 1981-08-05 EP disclosed
EP-0033215-A2 Process for preparing anti-allergy naphthotriazoles BEECHAM GROUP PLC (GB) 1981-08-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11613509-B2 Radical polymerization control agent and radical polymerization control method PPOX, NOX4, CROCC PIM1 1368/4885CDC25B 807/4885IDO1 2251/4885
US-20210122692-A1 RADICAL POLYMERIZATION CONTROL AGENT AND RADICAL POLYMERIZATION CONTROL METHOD PPOX, NOX4, CROCC PIM1 1368/4885CDC25B 807/4885IDO1 2251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.