⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31600086 | 0.77 | LMNA (0.32) | — | |
| SCHEMBL29571453 | 0.71 | — | — | |
| SCHEMBL31600910 | 0.69 | HPGD (0.35) | — | |
| SCHEMBL31600922 | 0.62 | — | — | |
| SCHEMBL7840715 | 0.59 | HTT (0.34) | — | |
| SCHEMBL7104501 | 0.58 | — | — | |
| SCHEMBL41047 | 0.57 | — | — | |
| SCHEMBL30051908 | 0.57 | — | — | |
| SCHEMBL474806 | 0.57 | — | — | |
| SCHEMBL1617849 | 0.55 | HTR6 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166153-B | Fused pyrazine derivatives as A2A/A2B inhibitors | 因赛特公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-117304191-A | Fused pyrazine derivatives as A2A/A2B inhibitors | 因赛特公司 | 2023-12-29 | — | — | CN | disclosed |
| US-7674791-B2 | Triazolopyrazines and methods of making and using the same | BIOGEN IDEC MA INC. (US) | 2010-03-09 | — | — | US | disclosed |
| US-20070010520-A1 | Triazolopyrazines and methods of making and using the same | BIOGEN IDEC MA INC. | 2007-01-11 | — | — | US | disclosed |
| EP-1615931-A1 | TRIAZOLOPYRAZINES AND METHODS OF MAKING AND USING THE SAME | Biogen Idec MA Inc. (US) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004092177-A1 | TRIAZOLOPYRAZINES AND METHODS OF MAKING AND USING THE SAME | BIOGEN IDEC MA INC. (US) | 2004-10-28 | — | — | WO | disclosed |