Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HMGCR | P04035 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL11514854 | 1.00 | FFAR3 (0.47) | FFAR3LCKFYNALDH1A1TSHR | |
| Bicarbonate SCHEMBL10646474 | 0.90 | TSHR (0.39) | FFAR3LCKFYNALDH1A1TSHR | |
| Acetone SCHEMBL1092423 | 0.90 | LMNA (0.43) | FFAR3LCKFYNALDH1A1TSHR | |
| Methacrylic Acid SCHEMBL11681478 | 0.87 | TET2 (0.37) | FFAR3LCKFYNTDP1 | |
| Acrylic Acid SCHEMBL11685831 | 0.84 | LMNA (0.48) | FFAR3LCKFYNALDH1A1TSHR | |
| Carbamic Acid SCHEMBL28125699 | 0.84 | ACHE (0.44) | FFAR3ALDH1A1TSHRHMGCRCHRM1 | |
| Methacrylic Acid SCHEMBL8383575 | 0.83 | TET2 (0.38) | FFAR3LCKFYNALDH1A1TSHR | |
| Methacrylic Acid SCHEMBL51595 | 0.83 | TET2 (0.38) | FFAR3LCKFYNALDH1A1TSHR | |
| Methacrylic Acid SCHEMBL135474 | 0.83 | TET2 (0.38) | FFAR3LCKFYNALDH1A1TSHR | |
| Methacrylic Acid SCHEMBL1494603 | 0.83 | TET2 (0.38) | FFAR3LCKFYNALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100035997-A1 | KIT FOR APPLYING A POLYMERIZABLE ADHESIVE COMPOSITION TO TISSUES | BROADLEY KENNETH N | 2010-02-11 | — | — | US | disclosed |
| US-20100029978-A1 | RAPIDLY CURING CYANOACRYLATES AS ADHESIVES | SWORDS NOELEEN | 2010-02-04 | — | — | US | disclosed |
| US-20060241226-A1 | GAP-FILLING CYANOACRYLATE ADHESIVE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2006-10-26 | — | — | US | disclosed |
| US-6703087-B1 | Thermal transfer material and image forming material using the same | FUJI PHOTO FILM CO., LTD. (JP) | 2004-03-09 | — | — | US | disclosed |
| US-6680089-B2 | Thermal transfer sheet | FUJI PHOTO FILM CO., LTD. (JP) | 2004-01-20 | — | — | US | disclosed |
| US-6617385-B1 | Alkylene biscyanoacrylate; addition polymer; ester plasticizer | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-09-09 | — | — | US | disclosed |
| US-6482768-B1 | Laser thermal transfer material | FUJI PHOTO FILM CO., LTD. (JP) | 2002-11-19 | — | — | US | disclosed |
| US-20020075228-A1 | Thermal transfer sheet | FUJI PHOTO FILM CO., LTD. | 2002-06-20 | — | — | US | disclosed |
| US-6326121-B1 | MULTILAYER; LIGHT TO HEAT CONVERSION LAYER AND IMAGE FORMING LAYER | FUJI PHOTO FILM CO., LTD. (JP) | 2001-12-04 | — | — | US | disclosed |
| US-20010004485-A1 | Thermal transfer sheet | FUJI PHOTO FILM CO., LTD. (JP) | 2001-06-21 | — | — | US | disclosed |
| US-6235445-B1 | IMAGE FORMING; OVERCOATING RECEIVER SHEET, RADIATION, TRANSFERRING | FUJI PHOTO FILM CO., LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035997-A1 | KIT FOR APPLYING A POLYMERIZABLE ADHESIVE COMPOSITION TO TISSUES | KIT, TEKT1, CUTA | FFAR3 1843/4885LCK 698/4885FYN 300/4885 |
| US-20100029978-A1 | RAPIDLY CURING CYANOACRYLATES AS ADHESIVES | ICAM1, ITGA1, ITGA5 | FFAR3 2081/4885LCK 2940/4885FYN 383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.