SCHEMBL31992

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL191370	0.84	ALDH1A1 (0.38)	KDM4EALDH1A1HPGDHSD17B10GFER
	SCHEMBL30649291	0.80	KDM4E (0.59)	KDM4EALDH1A1HPGDHSD17B10GFER
	SCHEMBL12362198	0.80	KDM4E (0.59)	KDM4EALDH1A1HPGDHSD17B10GFER
	SCHEMBL3392208	0.78	KDM4E (0.47)	KDM4EALDH1A1HPGDHSD17B10GFER
	SCHEMBL7608150	0.76	KDM4E (0.63)	KDM4EALDH1A1HPGDHSD17B10LMNA
	SCHEMBL192172	0.75	AGXT (0.42)	ALDH1A1KMT2AHSP90AB1HSP90AA1
	SCHEMBL27916481	0.73	ACHE (0.37)	KDM4EALDH1A1HSD17B10GFERLMNA
	SCHEMBL3796805	0.72	AGXT (0.41)	KDM4EALDH1A1HPGDHSD17B10GFER
	SCHEMBL11449654	0.72	KDM4E (0.46)	KDM4EALDH1A1HPGDHSD17B10GFER
	SCHEMBL14469765	0.72	LMNA (0.63)	KDM4EALDH1A1HPGDHSD17B10GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.