SCHEMBL3201225

SCHEMBL3201225

CCO[SiH](OCC)C(C)CCCNc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.47
ALDH1A1 P00352 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.35
KCNH3 Q9ULD8 3/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C19 P33261 1/20 0.34
HTR2A P28223 1/20 0.33
HRH1 P35367 1/20 0.33
PSEN1 P49768 1/20 0.33
PSEN2 P49810 1/20 0.33
APH1B Q8WW43 1/20 0.33
NCSTN Q92542 1/20 0.33
APH1A Q96BI3 1/20 0.33
PSENEN Q9NZ42 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
PPARG P37231 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28658048 0.85 MAPT (0.44) MAPTALDH1A1L3MBTL1KCNH3CYP1A2
SCHEMBL3195231 0.84 MAPT (0.50) MAPTALDH1A1L3MBTL1KCNH3CYP1A2
SCHEMBL3188639 0.84 GAA (0.51) MAPTALDH1A1L3MBTL1NPSR1TDP1
SCHEMBL16192536 0.81 MAPT (0.44) MAPTALDH1A1NPSR1TDP1SMN1; SMN2
SCHEMBL15643120 0.78 ALDH1A1 (0.43) MAPTALDH1A1PSEN1PSEN2APH1B
SCHEMBL2255790 0.75 ALDH1A1 (0.64) MAPTALDH1A1L3MBTL1KCNH3CYP3A4
SCHEMBL483772 0.74 ALDH1A1 (0.53) MAPTALDH1A1L3MBTL1KCNH3CYP1A2
SCHEMBL10606669 0.74 ALDH1A1 (0.57) MAPTALDH1A1L3MBTL1KCNH3CYP1A2
SCHEMBL722359 0.73 ALDH1A1 (0.52) MAPTALDH1A1L3MBTL1KCNH3CYP1A2
SCHEMBL3340543 0.72 SMN1; SMN2 (0.43) MAPTALDH1A1CYP1A2CYP2C19SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023097771-A1 EPOXY MOLDING COMPOUND OF MODIFIED SILICON DIOXIDE GRAFTED EPOXY RESIN, AND PREPARATION METHOD THEREFOR 中国科学院深圳先进技术研究院 2023-06-08 WO disclosed
US-20140113230-A1 POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION AND CURED FILM PREPARED THEREFROM ROHM & HAAS ELECT MAT (KR) 2014-04-24 US disclosed
US-7846998-B2 nonhalogenated and non-antimony sealant epoxy-resin molding material superior in flame resistance and still retaining reliability, for example, of moldability, reflow resistance, moisture resistance and high-temperature storage HITACHI CHEMICAL CO., LTD. (JP) 2010-12-07 US disclosed
US-7666953-B2 Phosphine-protonated haloaromatic compound accelerator with curing resin and curing agent HITACHI CHEMICAL CO, LTD. (JP) 2010-02-23 US disclosed
US-20090143511-A1 ENCAPSULATED EPOXY-RESIN MOLDING COMPOUND, AND ELECTRONIC COMPONENT DEVICE HITACHI CHEMICAL CO., LTD. (JP) 2009-06-04 US disclosed
US-20090137717-A1 ENCAPSULATED EPOXY RESIN COMPOSITION AND ELECTRONIC COMPONENT DEVICE HITACHI CHEMICAL CO., LTD. (JP) 2009-05-28 US disclosed
US-20090062430-A1 Epoxy Resin Composition for Sealing and Electronic Component Device HITACHI CHEMICAL CO., LTD. (JP) 2009-03-05 US disclosed
US-20090005480-A1 REACTION PRODUCT OF PHOSPHINE AND PROTONATED HALOARYL COMPOUND AND USE AS EPOXY CURING ACCELERATOR NAKAMURA SHINYA 2009-01-01 US disclosed
US-20080262135-A1 REACTION PRODUCT OF PHOSPHINE AND PROTONATED HALOARYL COMPOUND AND USE AS EPOXY CURING ACCELERATOR SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-10-23 US disclosed
US-20080234409-A1 nonhalogenated and non-antimony sealant epoxy-resin molding material superior in flame resistance and still retaining reliability, for example, of moldability, reflow resistance, moisture resistance and high-temperature storage HITACHI CHEMICAL CO., LTD. (JP) 2008-09-25 US disclosed
US-7397139-B2 Containing a curing agent and an inorganic filler, especially silica having a maximum diameter size of at least 32 mu m, an average particle size of 12 mu m or less and a specific surface area of 3.0 m2/g or more HITACHI CHEMICAL CO., LTD. (JP) 2008-07-08 US disclosed
US-20080039556-A1 Encapsulated Epoxy-Resin Molding Compound, And Electronic Component Device HITACHI CHEMICAL CO., LTD. (JP) 2008-02-14 US disclosed
US-20060214153-A1 Containing a curing agent and an inorganic filler, especially silica having a maximum diameter size of at least 32 mu m, an average particle size of 12 mu m or less and a specific surface area of 3.0 m2/g or more HITACHI CHEMICAL CO., LTD. (JP) 2006-09-28 US disclosed
US-20060014873-A1 Encapsulating epoxy resin composition, and electronic parts device using the same HITACHI CHEMICAL CO., LTD. (JP) 2006-01-19 US disclosed
US-20050267286-A1 Curing accelerator for curing resin, curing resin composition, electronic component device and method for producing phosphine derivative HITACHI CHEMICAL CO., LTD. (JP) 2005-12-01 US disclosed
US-20050222300-A1 Encapsulating epoxy resin composition, and electronic parts device using the same HITACHI CHEMICAL CO., LTD. (JP) 2005-10-06 US disclosed
US-20050165202-A1 Curing accelerator for curing resin, curing resin composition and electronic component device HITACHI CHEMICAL CO., LTD. (JP) 2005-07-28 US disclosed
WO-2003072655-A1 ENCAPSULATING EPOXY RESIN COMPOSITION, AND ELECTRONIC PARTS DEVICE USING THE SAME HITACHI CHEMICAL CO., LTD. (JP) 2003-09-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090005480-A1 REACTION PRODUCT OF PHOSPHINE AND PROTONATED HALOARYL COMPOUND AND USE AS EPOXY CURING ACCELERATOR HDHD5, EHMT2, HRH2 MAPT 4473/4885ALDH1A1 839/4885L3MBTL1 4020/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.