SCHEMBL3203126

SCHEMBL3203126

Cc1cc(OC(C)(C)C)cc(C)c1S(OS(=O)(=O)c1c(C(F)(F)F)c(C(F)(F)F)c(C(F)(F)F)c(C(F)(F)F)c1C(F)(F)F)(c1ccccc1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 1/20 0.32
PGR P06401 1/20 0.32
NR3C2 P08235 1/20 0.32
ABCC9 O60706 1/20 0.32
ABCC8 Q09428 1/20 0.32
KCNJ11 Q14654 1/20 0.32
KCNJ8 Q15842 1/20 0.32
HSD11B1 P28845 1/20 0.32
MAPT P10636 2/20 0.31
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
TSHR P16473 1/20 0.31
CYP2C19 P33261 1/20 0.31
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3195099 0.88 HSD11B1 (0.32) ABCC9ABCC8KCNJ11KCNJ8HSD11B1
SCHEMBL3183411 0.88 HSD11B1 (0.33) NR3C1PGRHSD11B1
SCHEMBL3195154 0.87 NR3C1 (0.33) NR3C1PGRNR3C2ABCC9ABCC8
SCHEMBL3183558 0.86 HSD11B1 (0.33) NR3C1PGRNR3C2HSD11B1MAPT
SCHEMBL3199775 0.86 CYP1A2 (0.42) NR3C1PGRNR3C2MAPTLMNA
SCHEMBL3182063 0.86 HSD11B1 (0.38) NR3C1PGRHSD11B1MAPTKDM4E
SCHEMBL3190292 0.86 KMT2A (0.37) NR3C1PGRNR3C2LMNANPSR1
SCHEMBL3193036 0.83 HSD11B1 (0.33) NR3C1PGRABCC9ABCC8KCNJ11
SCHEMBL3192154 0.83 KMT2A (0.34) HSD11B1LMNAMEN1KMT2ACYP1A2
SCHEMBL3202138 0.82 POLQ (0.34) NR3C1PGRABCC9ABCC8KCNJ11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206888-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2012-06-26 US disclosed
US-20100028800-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-04 US disclosed
EP-1953593-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2008-08-06 EP disclosed
US-7060414-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-06-13 US disclosed
US-20050158657-A1 Radiation-sensitive resin composition SUZUKI AKI (JP) 2005-07-21 US disclosed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US disclosed