SCHEMBL320225

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20280456	0.83	CA1 (0.40)	CA2CA1CA9CA3CA12
	SCHEMBL15867030	0.83	VCAM1 (0.52)	CA2CA1CA9CA3CA12
	SCHEMBL10571424	0.81	ALDH1A1 (0.39)	CA2CA1CA9CA12CA4
	SCHEMBL68413	0.80	KMT2A (0.48)	CA2CA1CA9CA12CA4
	SCHEMBL18688252	0.79	CA2 (0.62)	CA2CA1CA9CA3CA12
	SCHEMBL1369885	0.79	PTGS2 (0.46)	CA2CA1CA9CA3PTGS2
	SCHEMBL67606	0.77	SOS1 (0.50)	CA2SOS1PTGS2KMT2APTGS1
	SCHEMBL31689452	0.75	TDP1 (0.41)	CA2CA1CA9CA12CA4
	SCHEMBL30161644	0.75	TSHR (0.51)	ALDH1A1HSD17B10PTGS2KMT2APTGS1
	SCHEMBL31689441	0.75	TDP1 (0.41)	CA2CA1CA9CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.