SCHEMBL68413

SCHEMBL68413

O=S(=O)(Cl)c1ccc(F)c(F)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.48
TDP1 Q9NUW8 2/20 0.48
SOS1 Q07889 2/20 0.44
ALDH1A1 P00352 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42
CA12 O43570 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
ALDH3A1 P30838 1/20 0.40
SLC1A3 P43003 1/20 0.40
SLC1A2 P43004 1/20 0.40
SLC1A1 P43005 1/20 0.40
PTGS2 P35354 4/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6893360 0.88 KMT2A (0.41) KMT2ATDP1SOS1ALDH1A1CA1
SCHEMBL67606 0.82 SOS1 (0.50) KMT2ASOS1CA2PTGS2PTGS1
SCHEMBL10571424 0.82 ALDH1A1 (0.39) KMT2ATDP1SOS1ALDH1A1HSD17B10
SCHEMBL1940923 0.82 PTGS2 (0.42) TDP1SOS1ALDH1A1HSD17B10CA1
SCHEMBL5839980 0.80 CA1 (0.41) TDP1SOS1ALDH1A1HSD17B10CA1
SCHEMBL2780594 0.80 CA1 (0.47) KMT2ATDP1SOS1ALDH1A1HSD17B10
SCHEMBL733946 0.80 TSHR (0.51) KMT2AALDH1A1HSD17B10PTGS2PTGS1
SCHEMBL30161644 0.80 TSHR (0.51) KMT2AALDH1A1HSD17B10PTGS2PTGS1
SCHEMBL320225 0.80 CA2 (0.40) KMT2ATDP1SOS1ALDH1A1HSD17B10
SCHEMBL2778156 0.80 CA1 (0.68) KMT2ATDP1ALDH1A1HSD17B10CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 749 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4127157-B1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS ENCODIA INC (US) 2026-02-11 EP claimed
CN-119565410-A Seawater desalination reverse osmosis membrane, preparation method and application 湖南澳维膜科技有限公司 2025-03-07 CN claimed
CN-117624140-A CXCR4 antagonists, methods of making and uses thereof 杭州师范大学 2024-03-01 CN claimed
US-20240011009-A1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2024-01-11 US claimed
US-20230220589-A1 POLYPEPTIDE TERMINAL BINDERS AND USES THEREOF Encodia, Inc. (US) 2023-07-13 US claimed
EP-4127157-A1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2023-02-08 EP claimed
WO-2022072560-A1 POLYPEPTIDE TERMINAL BINDERS AND USES THEREOF Encodia, Inc. (US) 2022-04-07 WO claimed
WO-2021194908-A1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2021-09-30 WO claimed
EP-4743446-A1 NITRO-CONTAINING COMPOUNDS THAT KILL MYCOBACTERIA Board of Trustees of Michigan State University (US) 2026-05-20 EP disclosed
US-12630529-B2 GCN2 modulator compounds Alesta Therapeutics BV (NL) 2026-05-19 US disclosed
US-12570613-B2 Imidazoquinoline or benzoindazolone compound and intermediate for preparing same LMITO THERAPEUTICS INC. (KR) 2026-03-10 US disclosed
EP-4127157-B1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS ENCODIA INC (US) 2026-02-11 EP disclosed
CN-120640936-A Perovskite solar cell modified by 3, 4-difluorobenzenesulfonyl chloride 西南石油大学 2025-09-12 CN disclosed
CN-120640936-A Perovskite solar cell modified by 3, 4-difluorobenzenesulfonyl chloride 西南石油大学 2025-09-12 CN disclosed
US-5849926-A Pyrazole derivatives and herbicides containing the same IDEMITSU KOSAN CO., LTD. (JP) 1998-12-15 US disclosed
US-5756759-A HERBICIDES IDEMITSU KOSAN CO., LTD. (JP) 1998-05-26 US disclosed
EP-0728756-A1 PYRAZOLE DERIVATIVES AND HERBICIDE CONTAINING THE SAME IDEMITSU KOSAN COMPANY LIMITED (JP) 1996-08-28 EP disclosed
WO-1995032500-A1 SULFONAMIDES USEFUL AS LUBRICANTS IN MAGNETIC RECORDING MEDIA THE DOW CHEMICAL COMPANY (US) 1995-11-30 WO disclosed
US-5212301-A SUBSTITUTED FLUOROBENZENES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-05-18 US disclosed
EP-0512715-A2 Verfahren zur Herstellung einer in 3-Stellung fluorierten aromatischen Verbindung ZENECA LIMITED (GB) 1992-11-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630529-B2 GCN2 modulator compounds NR3C1, GCN1, EIF2AK4 KMT2A 3057/4885TDP1 3878/4885SOS1 2617/4885
US-12570613-B2 Imidazoquinoline or benzoindazolone compound and intermediate for preparing same NQO1, CBR1, NFE2L2 KMT2A 3455/4885TDP1 2395/4885SOS1 1911/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.