SCHEMBL3193036

SCHEMBL3193036

Cc1cccc(C)c1S(OS(=O)(=O)c1c(C(F)(F)F)c(C(F)(F)F)c(C(F)(F)F)c(C(F)(F)F)c1C(F)(F)F)(c1ccccc1)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.33
TDP1 Q9NUW8 1/20 0.32
MAPT P10636 3/20 0.32
ALDH1A1 P00352 2/20 0.32
POLB P06746 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
SDHB P21912 1/20 0.32
KAT6A Q92794 1/20 0.32
ABCC9 O60706 1/20 0.31
ABCC8 Q09428 1/20 0.31
KCNJ11 Q14654 1/20 0.31
KCNJ8 Q15842 1/20 0.31
NR1H3 Q13133 2/20 0.31
LMNA P02545 2/20 0.31
KDM4E B2RXH2 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
NR3C1 P04150 1/20 0.30
PGR P06401 1/20 0.30
AR P10275 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3199775 0.89 CYP1A2 (0.42) MAPTALDH1A1POLBSMN1; SMN2LMNA
SCHEMBL3203126 0.83 NR3C1 (0.32) HSD11B1MAPTALDH1A1POLBSMN1; SMN2
SCHEMBL3203657 0.83 HSD11B1 (0.40) HSD11B1MAPTALDH1A1POLBLMNA
SCHEMBL3194661 0.83 HSD11B1 (0.35) HSD11B1MAPTALDH1A1POLBKAT6A
SCHEMBL3191622 0.82 CA1 (0.38) TDP1MAPTALDH1A1KAT6ALMNA
SCHEMBL3194867 0.82 KMT2A (0.38) TDP1ALDH1A1KAT6ALMNAKMT2A
SCHEMBL3200054 0.82 FFAR4 (0.35) HSD11B1MAPTALDH1A1POLBSMN1; SMN2
SCHEMBL3191828 0.81 HTR6 (0.33) HSD11B1ALDH1A1CYP3A4CYP2C19CYP2C9
SCHEMBL3191940 0.80 ALDH1A1 (0.40) HSD11B1MAPTALDH1A1POLBABCC9
SCHEMBL3192565 0.78 TSHR (0.45) TDP1ALDH1A1KAT6ALMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206888-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2012-06-26 US disclosed
US-20100028800-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-04 US disclosed
EP-1953593-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2008-08-06 EP disclosed
US-7060414-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-06-13 US disclosed
US-20050158657-A1 Radiation-sensitive resin composition SUZUKI AKI (JP) 2005-07-21 US disclosed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US disclosed