Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | AGO2 | Q9UKV8 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13989375 | 1.00 | CA2 (0.49) | CA2GAATSHRALDH1A1NT5E | |
| SCHEMBL13989396 | 0.85 | CA2 (0.41) | CA2GAATSHRALDH1A1NT5E | |
| SCHEMBL13989394 | 0.85 | ALDH1A1 (0.41) | CA2GAAALDH1A1NT5ECYP3A4 | |
| SCHEMBL13989376 | 0.83 | GAA (0.49) | CA2GAATSHRALDH1A1NT5E | |
| SCHEMBL8368635 | 0.82 | HSD11B1 (0.47) | CA2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL13420590 | 0.82 | CA2 (0.35) | CA2GAACA1CA12CA7 | |
| SCHEMBL2148822 | 0.81 | CA2 (0.70) | CA2GAATSHRALDH1A1NT5E | |
| SCHEMBL13989387 | 0.81 | ALDH1A1 (0.49) | CA2TSHRALDH1A1LMNAHTR6 | |
| SCHEMBL3943010 | 0.81 | GAA (0.58) | CA2GAATSHRALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7996737 | 0.80 | CA2 (0.68) | CA2GAATSHRALDH1A1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7683208-B2 | Bridge compound with N,N-dialkylamino group and application thereof | EVERLIGHT USA, INC. (US) | 2010-03-23 | — | — | US | disclosed |
| US-20090054645-A1 | Bridge compound with N, N-dialkylamino group and application thereof | EVERLIGHT USA, INC. (US) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054645-A1 | Bridge compound with N, N-dialkylamino group and application thereof | ALKBH1, ALKBH2, B2M | CA2 3736/4885GAA 2927/4885TSHR 3731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.