SCHEMBL3204983

SCHEMBL3204983

Cc1ccc(S(OS(=O)(=O)c2ccccc2C(F)(F)F)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 5/20 0.46
SLC22A12 Q96S37 4/20 0.40
KMT2A Q03164 4/20 0.40
GAA P10253 3/20 0.40
CYP2C9 P11712 2/20 0.40
ALDH1A1 P00352 2/20 0.40
MEN1 O00255 2/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C19 P33261 1/20 0.40
SLC22A6 Q4U2R8 1/20 0.39
SLC22A8 Q8TCC7 1/20 0.39
SLC22A11 Q9NSA0 1/20 0.39
CA12 O43570 1/20 0.38
CA9 Q16790 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
F2 P00734 1/20 0.36
BCHE P06276 1/20 0.36
ACHE P22303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL451960 0.91 KMT2A (0.46) HSD11B1SLC22A12KMT2ACYP2C9ALDH1A1
SCHEMBL452885 0.88 HSD11B1 (0.51) HSD11B1SLC22A12KMT2ACYP2C9ALDH1A1
SCHEMBL3183368 0.86 GAA (0.52) HSD11B1SLC22A12KMT2AGAA
SCHEMBL3202409 0.85 HSD11B1 (0.43) HSD11B1SLC22A12KMT2ACYP2C9ALDH1A1
SCHEMBL3192056 0.85 HSD11B1 (0.43) HSD11B1SLC22A12KMT2AGAACYP2C9
SCHEMBL547991 0.84 MEN1 (0.48) HSD11B1SLC22A12KMT2AALDH1A1MEN1
SCHEMBL450234 0.83 KMT2A (0.54) HSD11B1SLC22A12KMT2AGAAMEN1
SCHEMBL15675641 0.83 HSD11B1 (0.48) HSD11B1SLC22A12KMT2ACYP2C9ALDH1A1
SCHEMBL2960439 0.81 HTT (0.41) HSD11B1KMT2AGAACYP2C9ALDH1A1
SCHEMBL3136049 0.80 BCHE (0.49) HSD11B1KMT2AGAAALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206888-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2012-06-26 US disclosed
US-20100028800-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-04 US disclosed
EP-1953593-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2008-08-06 EP disclosed
US-7060414-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-06-13 US disclosed
US-20050158657-A1 Radiation-sensitive resin composition SUZUKI AKI (JP) 2005-07-21 US disclosed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US disclosed