SCHEMBL3202409

SCHEMBL3202409

CCc1ccc(S(OS(=O)(=O)c2ccccc2C(F)(F)F)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 6/20 0.43
FFAR4 Q5NUL3 1/20 0.39
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 1/20 0.39
F2 P00734 1/20 0.39
MAPT P10636 1/20 0.39
VDR P11473 1/20 0.39
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
SLC22A12 Q96S37 4/20 0.36
CA2 P00918 1/20 0.36
CYP2C9 P11712 1/20 0.36
SLC22A6 Q4U2R8 1/20 0.36
SLC22A8 Q8TCC7 1/20 0.36
SLC22A11 Q9NSA0 1/20 0.36
PTGDR2 Q9Y5Y4 3/20 0.36
NR1H3 Q13133 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL451960 0.88 KMT2A (0.46) HSD11B1ALDH1A1KMT2AMEN1SLC22A12
SCHEMBL3204983 0.85 HSD11B1 (0.46) HSD11B1ALDH1A1F2KMT2AMEN1
SCHEMBL452885 0.84 HSD11B1 (0.51) HSD11B1FFAR4ALDH1A1KMT2AMEN1
SCHEMBL3183368 0.83 GAA (0.52) HSD11B1FFAR4KDM4EKMT2ASLC22A12
SCHEMBL3192056 0.82 HSD11B1 (0.43) HSD11B1ALDH1A1KDM4EKMT2AMEN1
SCHEMBL3201041 0.82 ALDH1A1 (0.43) HSD11B1ALDH1A1KDM4EF2MAPT
SCHEMBL3182566 0.80 ALDH1A1 (0.51) HSD11B1ALDH1A1KDM4EF2MAPT
SCHEMBL450234 0.80 KMT2A (0.54) HSD11B1FFAR4KDM4EMAPTKMT2A
SCHEMBL15675641 0.80 HSD11B1 (0.48) HSD11B1FFAR4ALDH1A1KMT2AMEN1
SCHEMBL5412457 0.80 PPARG (0.40) HSD11B1FFAR4ALDH1A1KDM4EF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206888-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2012-06-26 US disclosed
US-20100028800-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-04 US disclosed
EP-1953593-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2008-08-06 EP disclosed
US-7060414-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-06-13 US disclosed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US disclosed