SCHEMBL452885

SCHEMBL452885

CC(C)(C)c1ccc(S(OS(=O)(=O)c2ccccc2C(F)(F)F)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 12/20 0.51
ALDH1A1 P00352 2/20 0.41
HSD17B3 P37058 1/20 0.41
NPC1 O15118 1/20 0.41
RECQL P46063 1/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
FFAR1 O14842 1/20 0.39
FFAR4 Q5NUL3 1/20 0.39
NR1H3 Q13133 1/20 0.39
CYP2C9 P11712 1/20 0.38
SLC22A6 Q4U2R8 1/20 0.38
SLC22A8 Q8TCC7 1/20 0.38
SLC22A12 Q96S37 1/20 0.38
SLC22A11 Q9NSA0 1/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL451960 0.90 KMT2A (0.46) HSD11B1ALDH1A1RAB9AKMT2AMEN1
SCHEMBL3204983 0.88 HSD11B1 (0.46) HSD11B1ALDH1A1KMT2AMEN1CYP2C9
SCHEMBL3183368 0.85 GAA (0.52) HSD11B1KMT2AFFAR4SLC22A12
SCHEMBL3134871 0.85 HSD11B1 (0.47) HSD11B1ALDH1A1HSD17B3NPC1RECQL
SCHEMBL3134802 0.85 HSD11B1 (0.47) HSD11B1ALDH1A1HSD17B3NPC1RECQL
SCHEMBL3202409 0.84 HSD11B1 (0.43) HSD11B1ALDH1A1KMT2AMEN1FFAR4
SCHEMBL3192056 0.84 HSD11B1 (0.43) HSD11B1ALDH1A1KMT2AMEN1CYP2C9
SCHEMBL451539 0.82 HSD11B1 (0.53) HSD11B1ALDH1A1HSD17B3NPC1RECQL
SCHEMBL2634260 0.82 HSD11B1 (0.53) HSD11B1ALDH1A1HSD17B3NPC1RECQL
SCHEMBL450234 0.82 KMT2A (0.54) HSD11B1KMT2AMEN1FFAR4SLC22A12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3010943-B1 CURABLE COMPOSITION, FILM, AND METHOD OF PRODUCING FILM CANON KK (JP) 2024-04-03 EP disclosed
EP-2841255-B1 RESIN PRODUCTION METHOD AND RESIN PRODUCTION APPARATUS CANON KK (JP) 2020-05-13 EP disclosed
US-10472445-B2 Photocurable composition and method for manufacturing film CANON KABUSHIKI KAISHA (JP) 2019-11-12 US disclosed
US-10421853-B2 Photosensitive gas generating agent and photocurable composition CANON KABUSHIKI KAISHA (JP) 2019-09-24 US disclosed
EP-2758987-B1 METHOD OF FORMING A FILM CANON KK (JP) 2019-03-20 EP disclosed
US-10208183-B2 Curable composition, film, and method of producing film CANON KABUSHIKI KAISHA (JP) 2019-02-19 US disclosed
US-9982102-B2 Photocurable composition and method of manufacturing film using the composition CANON KABUSHIKI KAISHA (JP) 2018-05-29 US disclosed
US-9961776-B2 Method of producing cured product and method of forming pattern CANON KABUSHIKI KAISHA (JP) 2018-05-01 US disclosed
EP-2847235-B1 PHOTOCURABLE COMPOSITION AND METHOD OF MANUFACTURING FILM USING THE COMPOSITION CANON KK (JP) 2017-11-22 EP disclosed
EP-2850650-B1 PHOTOCURABLE COMPOSITION AND METHOD FOR MANUFACTURING A FILM CANON KK (JP) 2017-09-20 EP disclosed
CN-1643021-A Polyalkenyl ether resin KYOWA YUKA KK (JP) 2005-07-20 CN disclosed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US disclosed
US-20050095527-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-05 US disclosed
EP-0959389-B1 Diazodisulfone compound and radiation-sensitive resin composition JSR CORP (JP) 2004-03-31 EP disclosed
US-6623907-B2 Chemical amplified photoresist JSR CORPORATION (JP) 2003-09-23 US disclosed
US-6337171-B1 AS A RESIST APPLICABLE TO FAR ULTRAVIOLET RAYS SUCH AS A KRF EXCIMER LASER, CHARGED PARTICLE RAYS SUCH AS ELECTRON BEAMS, AND X-RAYS JSR CORPORATION (JP) 2002-01-08 US disclosed
US-20010023050-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2001-09-20 US disclosed
US-6143460-A PHOTOACID GENERATOR PROVIDING IMPROVED PHOTORESIST RESOLUTION JSR CORPORATION (JP) 2000-11-07 US disclosed
EP-1011029-A2 Radiation-sensitive resin composition JSR Corporation (JP) 2000-06-21 EP disclosed
EP-0959389-A1 Diazodisulfone compound and radiation-sensitive resin composition JSR Corporation (JP) 1999-11-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10421853-B2 Photosensitive gas generating agent and photocurable composition PFN1, PFAS, FRG1 HSD11B1 4332/4885ALDH1A1 4165/4885HSD17B3 4273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.