Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30539313 | 1.00 | CA2 (0.40) | CA2NISCHABCG2ITGB2ICAM1 | |
| SCHEMBL23219954 | 0.71 | CA2 (0.34) | CA2NISCHHTR1AADRA2ADRD1 | |
| SCHEMBL9877616 | 0.71 | POLB (0.41) | CA2NISCH | |
| SCHEMBL1890902 | 0.69 | NISCH (0.53) | CA2NISCHABCG2ITGB2ICAM1 | |
| SCHEMBL437597 | 0.69 | CA2 (0.50) | CA2NISCHITGB2ICAM1ITGAL | |
| SCHEMBL11307666 | 0.69 | ABCG2 (0.36) | CA2NISCHABCG2ITGB2ICAM1 | |
| SCHEMBL3072276 | 0.69 | MAOA (0.46) | CA2NISCHABCG2ITGB2ICAM1 | |
| SCHEMBL312107 | 0.69 | ABCG2 (0.36) | CA2NISCHABCG2ITGB2ICAM1 | |
| SCHEMBL3655783 | 0.69 | ABCG2 (0.36) | CA2NISCHABCG2ITGB2ICAM1 | |
| SCHEMBL329447 | 0.69 | MAOA (0.46) | CA2NISCHABCG2ITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537519-B1 | Method for the preparation of fluoro substituted aminobenzodioxoles and -benzodioxanes and intermediates | BAYER AG (DE) | 1997-06-04 | — | — | EP | claimed |
| EP-0375977-B1 | Oxidation hairdyeing composition based upon diaminopyrazole derivatives, and these diaminopyrazole derivatives | WELLA AG (DE) | 1994-02-02 | — | — | EP | claimed |
| US-5260460-A | Process for the preparation of fluorine-substituted aminobenzodioxoles and -benzodioxanes and new intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | claimed |
| CN-117534682-A | Monofunctional bio-based benzoxazine monomer with multi-benzodioxole structure and resin | 江苏大学 | 2024-02-09 | — | — | CN | disclosed |
| US-20230257390-A1 | COMPOUNDS WHICH INHIBIT RNA POLYMERASE AND THEIR USE | LIEBER INSTITUTE, INC. | 2023-08-17 | — | — | US | disclosed |
| EP-3284832-B1 | APTAMER WITH IMPROVED RATE OF DISSOCIATION, AND NON-COVALENT APTAMER-TARGET COMPLEX THEREOF | SOMALOGIC OPERATING CO INC (US) | 2023-06-07 | — | — | EP | disclosed |
| US-11111495-B2 | Method for generating aptamers with improved off-rates | SOMALOGIC, INC. (US) | 2021-09-07 | — | — | US | disclosed |
| US-20190330634-A1 | Method for Generating Aptamers with Improved Off-Rates | SOMALOGIC OPERATING CO., INC. | 2019-10-31 | — | — | US | disclosed |
| US-20190264208-A1 | Method for Generating Aptamers with Improved Off-Rates | SOMALOGIC, INC. | 2019-08-29 | — | — | US | disclosed |
| US-10316321-B2 | Method for generating aptamers with improved off-rates | SOMALOGIC INC. (US) | 2019-06-11 | — | — | US | disclosed |
| US-20180155725-A1 | Method for Generating Aptamers with Improved Off-Rates | SOMALOGIC, INC. (US) | 2018-06-07 | — | — | US | disclosed |
| WO-1995033719-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1995-12-14 | — | — | WO | disclosed |
| US-5260460-A | Process for the preparation of fluorine-substituted aminobenzodioxoles and -benzodioxanes and new intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | disclosed |
| US-5260460-A | Process for the preparation of fluorine-substituted aminobenzodioxoles and -benzodioxanes and new intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | disclosed |
| US-5260460-A | Process for the preparation of fluorine-substituted aminobenzodioxoles and -benzodioxanes and new intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | disclosed |
| EP-0537519-A1 | Method for the preparation of fluoro substituted aminobenzodioxoles and -benzodioxanes and intermediates | BAYER AG (DE) | 1993-04-21 | — | — | EP | disclosed |
| EP-0537519-A1 | Method for the preparation of fluoro substituted aminobenzodioxoles and -benzodioxanes and intermediates | BAYER AG (DE) | 1993-04-21 | — | — | EP | disclosed |
| EP-0537519-A1 | Method for the preparation of fluoro substituted aminobenzodioxoles and -benzodioxanes and intermediates | BAYER AG (DE) | 1993-04-21 | — | — | EP | disclosed |
| US-5021066-A | Alloys for slow release of ammonia; discoloration inhibition | WELLA AKTIENGESELLSCHAFT (DE) | 1991-06-04 | — | — | US | disclosed |
| US-4155915-A | POSTEMERGENCE AND PREEMERGENCE HERBICIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257390-A1 | COMPOUNDS WHICH INHIBIT RNA POLYMERASE AND THEIR USE | POLR2E, POLR2H, POLRMT | CA2 2458/4885NISCH 4625/4885ABCG2 1583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.