SCHEMBL3206290

SCHEMBL3206290

CC(C)(C)Oc1cc(OC(C)(C)C)cc(S(OS(=O)(=O)c2c(F)c(F)c(F)c(F)c2F)(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA7 P43166 2/20 0.33
CA13 Q8N1Q1 2/20 0.33
LOX P28300 1/20 0.31
HSD11B1 P28845 1/20 0.31
PTGES2 Q9H7Z7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6760272 0.91 PTGES2 (0.36) CA12CA1CA2CA7CA13
SCHEMBL2903713 0.90 CA1 (0.35) CA12CA1CA2CA7CA13
SCHEMBL8083696 0.90 CA1 (0.35) CA12CA1CA2CA7CA13
SCHEMBL3195455 0.89 LMNA (0.33) LOXHSD11B1PTGES2
SCHEMBL3182670 0.88 CA12 (0.32) CA12CA1CA2CA7CA13
SCHEMBL3195154 0.88 NR3C1 (0.33) CA12CA1CA2CA7CA13
SCHEMBL8651808 0.87 PTGES2 (0.34) CA12CA1CA2CA7CA13
SCHEMBL3183411 0.86 HSD11B1 (0.33) LOXHSD11B1PTGES2
SCHEMBL3206111 0.85 KMT2A (0.36) HSD11B1
SCHEMBL5406984 0.84 CA1 (0.36) CA12CA1CA2CA7HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206888-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2012-06-26 US disclosed
US-20100028800-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-04 US disclosed
EP-1953593-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2008-08-06 EP disclosed
US-7060414-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-06-13 US disclosed
US-20050158657-A1 Radiation-sensitive resin composition SUZUKI AKI (JP) 2005-07-21 US disclosed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US disclosed