Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 5/20 | 0.32 |
| ▸ | HTR2A | P28223 | 5/20 | 0.32 |
| ▸ | DRD3 | P35462 | 5/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3225548 | 0.85 | HTR6 (0.34) | ALDH1A1HTTDRD2HTR2ADRD3 | |
| SCHEMBL3217881 | 0.83 | HTR6 (0.35) | DRD2HTR2APDE10AHTR6 | |
| SCHEMBL3215962 | 0.83 | ALOX15 (0.34) | ALDH1A1HTTDRD2HTR2ADRD3 | |
| SCHEMBL3214873 | 0.83 | HTR6 (0.34) | ALDH1A1HTTDRD2HTR2ADRD3 | |
| SCHEMBL13424901 | 0.77 | ALDH1A1 (0.34) | ALDH1A1HTTDRD2HTR2AHTR6 | |
| SCHEMBL3215933 | 0.73 | HTR6 (0.34) | DRD2HTR2ADRD3PDE10AHTR6 | |
| SCHEMBL3217661 | 0.72 | MTNR1A (0.41) | MTNR1AMTNR1B | |
| SCHEMBL3225017 | 0.71 | HTR6 (0.33) | ALDH1A1HTTDRD2HTR2ADRD3 | |
| SCHEMBL3221756 | 0.71 | HTR6 (0.35) | ALDH1A1HTTDRD2HTR2AMTNR1A | |
| SCHEMBL3222807 | 0.70 | MTNR1A (0.42) | DRD2HTR2ADRD3MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056491-A1 | 4'-AMINO CYCLIC COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056491-A1 | 4'-AMINO CYCLIC COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | HTR6, HTR4, HTR3B | TSHR 317/4885ALDH1A1 1900/4885GFER 1251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.