Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PROC | P04070 | 1/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3221049 | 0.96 | AGTR2 (0.45) | AGTR2POLBLMNAPKMCFTR | |
| SCHEMBL28560316 | 0.86 | CFTR (0.57) | POLBLMNAPKMCFTRTDP1 | |
| SCHEMBL29409296 | 0.86 | CFTR (0.57) | POLBLMNAPKMCFTRTDP1 | |
| SCHEMBL4111979 | 0.80 | TDP1 (0.62) | POLBLMNAPKMCFTRTDP1 | |
| SCHEMBL3200492 | 0.79 | FFAR2 (0.46) | FFAR2 | |
| SCHEMBL774094 | 0.79 | FFAR2 (0.46) | FFAR2 | |
| SCHEMBL13423748 | 0.78 | CFTR (0.43) | LMNAPKMCFTRF10PRSS1 | |
| SCHEMBL8495772 | 0.78 | LMNA (0.61) | POLBLMNAPKMCFTRTDP1 | |
| SCHEMBL4108015 | 0.77 | LMNA (0.50) | POLBLMNAPKMCFTRTDP1 | |
| SCHEMBL3197745 | 0.77 | GLP1R (0.42) | LMNAPKMCFTRF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7683097-B2 | Topoisomerase inhibitors | Propharmacon Inc. (US) | 2010-03-23 | — | — | US | claimed |