Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 3/20 | 0.62 |
| ▸ | RXRA | P19793 | 2/20 | 0.60 |
| ▸ | RXRB | P28702 | 2/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.50 |
| ▸ | MARS1 | P56192 | 1/20 | 0.49 |
| ▸ | TDP2 | O95551 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.49 |
| ▸ | AXL | P30530 | 1/20 | 0.48 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.48 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.48 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.48 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.48 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.48 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6254589 | 0.86 | RXRA (0.59) | KMORXRARXRBSRD5A2HSD17B1 | |
| SCHEMBL2044221 | 0.86 | SRD5A2 (0.60) | KMORXRARXRBSRD5A2HSD17B1 | |
| SCHEMBL3540530 | 0.84 | KMO (0.66) | KMORXRARXRBMAP4K4LMNA | |
| SCHEMBL442436 | 0.83 | SRD5A2 (0.62) | KMORXRARXRBSRD5A2MAP4K4 | |
| SCHEMBL2371293 | 0.83 | KMO (0.61) | KMORXRARXRB | |
| SCHEMBL3220396 | 0.82 | KMO (0.91) | KMORXRARXRBLMNAGAA | |
| SCHEMBL6253145 | 0.80 | SRD5A2 (0.72) | RXRARXRBSRD5A2MAP4K4HSD17B1 | |
| SCHEMBL23296152 | 0.80 | RXRA (0.60) | KMORXRARXRBMAP4K4LMNA | |
| SCHEMBL14683877 | 0.80 | KMO (0.87) | KMORXRARXRBTDP2LMNA | |
| SCHEMBL29577419 | 0.80 | KMO (0.87) | KMORXRARXRBTDP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7683097-B2 | Topoisomerase inhibitors | Propharmacon Inc. (US) | 2010-03-23 | — | — | US | claimed |