Propylene Oxide

Propylene Oxide

SCHEMBL3208172

CC(c1ccccc1)S(=O)(=O)NC(=O)O.CC1CO1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.39
HPGD P15428 5/20 0.38
GAA P10253 1/20 0.38
P2RY12 Q9H244 1/20 0.37
RECQL P46063 1/20 0.36
LMNA P02545 2/20 0.36
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.36
GMNN O75496 1/20 0.36
MAPT P10636 1/20 0.36
PMP22 Q01453 1/20 0.36
KMT2A Q03164 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
APAF1 O14727 1/20 0.36
GRM7 Q14831 2/20 0.35
APLNR P35414 2/20 0.35
SLC6A3 Q01959 2/20 0.35
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2392454 0.87 KMT2A (0.43) POLBHPGDLMNAALDH1A1KDM4E
SCHEMBL22193557 0.74 KMT2A (0.46) POLBHPGDGAALMNAALDH1A1
Isopropylbenzene SCHEMBL27621981 0.71 CHRM2 (0.39) POLBHPGDGAALMNAALDH1A1
Phenyl Ethanol SCHEMBL27970674 0.70 KDM4E (0.42) POLBLMNAALDH1A1KDM4EKMT2A
SCHEMBL6635997 0.70 CYP2C19 (0.55) POLBHPGDLMNAALDH1A1KDM4E
SCHEMBL13189591 0.69 ALDH1A1 (0.44) POLBHPGDLMNAALDH1A1KDM4E
Isopropylbenzene SCHEMBL29066301 0.69 CHRM1 (0.40) POLBHPGDGAA
SCHEMBL16503498 0.69 ALDH1A1 (0.44) POLBHPGDLMNAALDH1A1KDM4E
SCHEMBL4621060 0.68 ADAMTS4 (0.53) POLBHPGDLMNAALDH1A1KDM4E
SCHEMBL4619215 0.68 ADAMTS4 (0.53) POLBHPGDLMNAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2018365-B1 NEW MATERIALS FOR LITHOGRAPHIC PLATES COATINGS, LITHOGRAPHIC PLATES AND COATINGS CONTAINING SAME, METHODS OF PREPARATION AND USE AMERICAN DYE SOURCE INC (CA) 2014-11-19 EP claimed
US-8323867-B2 Materials for lithographic plates coatings, lithographic plates and coatings containing same, methods of preparation and use AMERICAN DYE SOURCE, INC. (CA) 2012-12-04 US claimed
US-20100035183-A1 MATERIALS FOR LITHOGRAPHIC PLATES COATINGS, LITHOGRAPHIC PLATES AND COATINGS CONTAINING SAME, METHODS OF PREPARATION AND USE AMERICAN DYE SOURCE, INC. (CA) 2010-02-11 US claimed