Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | MMP3 | P08254 | 3/20 | 0.43 |
| ▸ | MMP13 | P45452 | 3/20 | 0.43 |
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | MMP7 | P09237 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MME | P08473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4619215 | 1.00 | ADAMTS4 (0.53) | ADAMTS4HTTMMP2MMP3MMP13 | |
| SCHEMBL10371824 | 0.81 | ALDH1A1 (0.42) | HTTLMNAPOLBKDM4EGMNN | |
| SCHEMBL4619146 | 0.80 | PKLR (0.43) | ADAMTS4MMP2MMP3MMP13MMP1 | |
| SCHEMBL4621582 | 0.80 | PKLR (0.43) | ADAMTS4MMP2MMP3MMP13MMP1 | |
| SCHEMBL28258812 | 0.79 | ALDH1A1 (0.50) | LMNAPOLBKDM4EGMNNALDH1A1 | |
| SCHEMBL2392454 | 0.78 | KMT2A (0.43) | SRCLMNAPOLBKDM4EGMNN | |
| SCHEMBL16503498 | 0.77 | ALDH1A1 (0.44) | SRCLMNAPOLBKDM4EGMNN | |
| SCHEMBL13189591 | 0.77 | ALDH1A1 (0.44) | SRCLMNAPOLBKDM4EGMNN | |
| SCHEMBL22193557 | 0.75 | KMT2A (0.46) | SRCLMNAPOLBKDM4EGMNN | |
| SCHEMBL18028795 | 0.75 | KMT2A (0.47) | LMNAPOLBKDM4EGMNNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1884230-A1 | PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT OR AGENT FOR PREVENTING/AMELIORATING ROUGH SKIN AND EXTERNAL COMPOSITION FOR SKIN | Shiseido Company, Limited (JP) | 2008-02-06 | — | — | EP | disclosed |