Sugi Predict

Sugi Predict / Compounds / SCHEMBL320862

SCHEMBL320862

SCHEMBL320862

NC(=NO)c1ccc(CO)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRSS1 P07477 1/20 0.56
▸ PRSS2 P07478 1/20 0.56
▸ PRSS3 P35030 1/20 0.56
▸ RAB9A P51151 3/20 0.47
▸ GAA P10253 2/20 0.47
▸ KDM1A O60341 4/20 0.47
▸ NOS3 P29474 1/20 0.45
▸ NOS1 P29475 1/20 0.45
▸ NPC1 O15118 2/20 0.43
▸ LMNA P02545 2/20 0.43
▸ TP53 P04637 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ ALOX15 P16050 1/20 0.43
▸ HSD17B10 Q99714 1/20 0.43
▸ GFER P55789 2/20 0.41
▸ USP2 O75604 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9968927 1.00 PRSS1 (0.56) PRSS1PRSS2PRSS3RAB9AGAA
SCHEMBL320861 1.00 PRSS1 (0.56) PRSS1PRSS2PRSS3RAB9AGAA
SCHEMBL319144 0.83 CA2 (0.46) PRSS1PRSS2PRSS3RAB9AGAA
SCHEMBL774619 0.83 CA2 (0.46) PRSS1PRSS2PRSS3RAB9AGAA
SCHEMBL21215222 0.83 KDM1A (0.60) RAB9AGAAKDM1ANPC1LMNA
SCHEMBL4253164 0.82 LOXL2 (0.56) RAB9AGAAKDM1ANOS3NOS1
SCHEMBL5154701 0.82 LOXL2 (0.56) RAB9AGAAKDM1ANOS3NOS1
SCHEMBL4253161 0.82 LOXL2 (0.56) RAB9AGAAKDM1ANOS3NOS1
Hydrochloric Acid SCHEMBL6743124 0.80 LOXL2 (0.54) RAB9AGAAKDM1ANOS3NOS1
Hydrochloric Acid SCHEMBL18300737 0.80 LOXL2 (0.54) RAB9AGAAKDM1ANOS3NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606548-B2 Fungicidal oxadiazoles FMC CORPORATION (US) 2026-04-21 — — US disclosed
US-20240166638-A1 FUNGICIDAL OXADIAZOLES FMC CORP (US) 2024-05-23 — — US disclosed
EP-4361150-A2 FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES FMC Corporation (US) 2024-05-01 — — EP disclosed
US-20240090503-A1 FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES FMC CORPORATION 2024-03-21 — — US disclosed
EP-4262396-A1 FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES FMC CORPORATION (US) 2023-10-25 — — EP disclosed
US-11708358-B2 Fungicidal oxadiazoles FMC CORPORATION (US) 2023-07-25 — — US disclosed
WO-2022133114-A1 FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES FMC CORPORATION (US) 2022-06-23 — — WO disclosed
EP-3957636-A1 FUNGICIDAL OXADIAZOLES FMC Corporation (US) 2022-02-23 — — EP disclosed
EP-3606920-B1 FUNGICIDAL OXADIAZOLES FMC CORP (US) 2021-09-22 — — EP disclosed
US-10676467-B2 Compositions for binding sphingosine-1-phosphate receptor 1 (S1P1), imaging of S1P1, and methods of use thereof WASHINGTON UNIVERSITY (US) 2020-06-09 — — US disclosed
EP-2193125-A2 OXADIAZOLE DERIVATIVES Merck Serono S.A. (CH) 2010-06-09 — — EP disclosed
EP-2170850-A1 NOVEL DICARBOXYLIC ACID DERIVATIVES AS S1P1 RECEPTOR AGONISTS BIOPROJET (FR) 2010-04-07 — — EP disclosed
WO-2010033701-A2 INHIBITORS OF SPHINGOSINE KINASE 1 GENZYME CORPORATION (US) 2010-03-25 — — WO disclosed
US-20100048639-A1 OXADIAZOLE DERIVATES AS S1P1 RECEPTOR AGONISTS GLAXO GROUP LIMITED (GB) 2010-02-25 — — US disclosed
WO-2009080663-A1 TRIAZOLE OXADIAZOLES DERIVATIVES MERCK SERONO S.A. (CH) 2009-07-02 — — WO disclosed
WO-2009043889-A2 OXADIAZOLE DERIVATIVES MERCK SERONO S.A. (CH) 2009-04-09 — — WO disclosed
WO-2008152149-A1 NOVEL DICARBOXYLIC ACID DERIVATIVES AS S1P1 RECEPTOR AGONISTS BIOPROJET (FR) 2008-12-18 — — WO disclosed
US-20080207584-A1 Compound Having S1P Receptor Binding Potency and Use Thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2008-08-28 — — US disclosed
EP-1826197-A1 AMINOCARBOXYLIC ACID DERIVATIVE AND MEDICINAL USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2007-08-29 — — EP disclosed
EP-1760071-A1 COMPOUND HAVING S1P RECEPTOR BINDING POTENCY AND USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2007-03-07 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240166638-A1 FUNGICIDAL OXADIAZOLES OXA1L, NOX1, TH PRSS1 4316/4885PRSS2 4653/4885PRSS3 4378/4885
US-20100048639-A1 OXADIAZOLE DERIVATES AS S1P1 RECEPTOR AGONISTS S1PR1, S1PR3, S1PR2 PRSS1 1822/4885PRSS2 4345/4885PRSS3 3659/4885
US-12606548-B2 Fungicidal oxadiazoles AOC2, AOC3, MT-CO3 PRSS1 4678/4885PRSS2 3999/4885PRSS3 3891/4885
US-20240090503-A1 FUNGICIDAL OXADIAZOLES AND THEIR MIXTURES NOX1, TH, NOX3 PRSS1 4499/4885PRSS2 4605/4885PRSS3 4234/4885
US-20080207584-A1 Compound Having S1P Receptor Binding Potency and Use Thereof S1PR1, EDNRA, S1PR3 PRSS1 1342/4885PRSS2 4280/4885PRSS3 4075/4885
US-10676467-B2 Compositions for binding sphingosine-1-phosphate receptor 1 (S1P1), imaging of S1P1, and methods of use thereof S1PR1, S1PR2, S1PR3 PRSS1 1611/4885PRSS2 4108/4885PRSS3 4087/4885
US-11708358-B2 Fungicidal oxadiazoles OXA1L, NOX1, TH PRSS1 4316/4885PRSS2 4653/4885PRSS3 4378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.