Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 6/20 | 0.63 |
| ▸ | CTSK | P43235 | 4/20 | 0.63 |
| ▸ | REN | P00797 | 2/20 | 0.62 |
| ▸ | CTSL | P07711 | 3/20 | 0.61 |
| ▸ | CTSS | P25774 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | TACR1 | P25103 | 2/20 | 0.59 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | CTSD | P07339 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489933 | 0.98 | CTSB (0.63) | CTSBCTSKRENCTSLCTSS | |
| SCHEMBL3210676 | 0.90 | CTSB (0.60) | CTSBCTSKCTSLCTSSCASP3 | |
| SCHEMBL13823620 | 0.90 | CTSB (0.60) | CTSBCTSKCTSLCTSSCASP3 | |
| SCHEMBL7327620 | 0.90 | CAPN1 (0.64) | CTSBCTSKRENCTSLCTSS | |
| SCHEMBL5686620 | 0.89 | REN (0.65) | CTSBCTSKRENCTSLCTSS | |
| SCHEMBL7275434 | 0.89 | ECE1 (0.65) | CTSBCTSKRENCTSLCTSS | |
| SCHEMBL9416814 | 0.88 | ALDH1A1 (0.62) | CTSBCTSKCTSLCTSSALDH1A1 | |
| SCHEMBL11450356 | 0.87 | CTSB (0.65) | CTSBCTSKRENCTSLCTSS | |
| SCHEMBL11450355 | 0.87 | CTSB (0.65) | CTSBCTSKRENCTSLCTSS | |
| SCHEMBL17902640 | 0.87 | CTSK (0.61) | CTSBCTSKCTSLCTSSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389764-B2 | Urea and sulfamide derivatives as inhibitors of TAFIa | SANOFI (FR) | 2013-03-05 | — | — | US | disclosed |
| US-20100035930-A1 | UREA AND SULFAMIDE DERIVATIVES AS INHIBITORS OF TAFIa | SANOFI-AVENTIS (FR) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035930-A1 | UREA AND SULFAMIDE DERIVATIVES AS INHIBITORS OF TAFIa | TFPI, TFPI2, SERPINE1 | CTSB 130/4885CTSK 209/4885REN 168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.