Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 2/20 | 0.65 |
| ▸ | MME | P08473 | 1/20 | 0.65 |
| ▸ | CTSB | P07858 | 4/20 | 0.65 |
| ▸ | CTSL | P07711 | 4/20 | 0.65 |
| ▸ | CTSK | P43235 | 2/20 | 0.65 |
| ▸ | CTSS | P25774 | 1/20 | 0.65 |
| ▸ | TACR1 | P25103 | 2/20 | 0.62 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.60 |
| ▸ | REN | P00797 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30420986 | 0.91 | MME (0.64) | ECE1MMECTSBCTSLCTSK | |
| SCHEMBL8489933 | 0.91 | CTSB (0.63) | CTSBCTSLCTSKCTSSTACR1 | |
| SCHEMBL7327620 | 0.91 | CAPN1 (0.64) | ECE1MMECTSBCTSLCTSK | |
| SCHEMBL3209669 | 0.90 | ECE1 (0.64) | ECE1MMECTSBCTSLCTSK | |
| SCHEMBL7327445 | 0.89 | CTSL (0.61) | CTSBCTSLCTSKCTSSTACR1 | |
| SCHEMBL3209667 | 0.89 | CTSB (0.63) | CTSBCTSLCTSKCTSSTACR1 | |
| SCHEMBL7327439 | 0.89 | CTSL (0.61) | CTSBCTSLCTSKCTSSTACR1 | |
| SCHEMBL7355802 | 0.89 | CTSK (0.74) | CTSBCTSLCTSKCTSSCAPN1 | |
| SCHEMBL7355798 | 0.89 | CTSK (0.74) | CTSBCTSLCTSKCTSSCAPN1 | |
| SCHEMBL7365480 | 0.88 | ECE1 (0.57) | ECE1MMECTSBCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111675666-B | (tetrazol-1-yl) -N, N, N ', N' -tetramethylurea hexafluorophosphate and preparation method thereof | 苏州昊帆生物股份有限公司 | 2022-05-17 | — | — | CN | disclosed |
| EP-0317645-B1 | 4H-3,1-BENZOXAZIN-4-ONE COMPOUNDS AND SERINE PROTEASE-INHIBITING MEDICINAL COMPOSITION CONTAINING SAME | TEIJIN LIMITED (JP) | 1993-09-15 | — | — | EP | disclosed |
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |
| US-4308201-A | SUBSTRATES; MEDICAL DIAGNOSIS | TORII & CO., LTD. (JP) | 1981-12-29 | — | — | US | disclosed |