Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | JAK1 | P23458 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | PLEC | Q15149 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3211432 | 0.85 | JAK2 (0.49) | JAK2JAK1MAPTP2RX1RXFP1 | |
| SCHEMBL3212463 | 0.83 | RORC (0.48) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL13455970 | 0.80 | LMNA (0.43) | MAPTALDH1A1KDM4EGAATHRB | |
| SCHEMBL3226967 | 0.79 | AR (0.36) | MAPTALDH1A1KDM4EGAAMAPK1 | |
| SCHEMBL13490738 | 0.78 | CISD2 (0.36) | JAK2JAK1EPHX2MAPTALDH1A1 | |
| SCHEMBL3209175 | 0.77 | RXFP1 (0.46) | JAK2JAK1MAPTMEN1KMT2A | |
| SCHEMBL3211447 | 0.74 | PTGS1 (0.42) | MAPTALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL1843940 | 0.73 | PTGS1 (0.56) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL3205565 | 0.73 | LMNA (0.36) | MAPTALDH1A1KDM4EGAAMAPK1 | |
| SCHEMBL11987617 | 0.72 | PTGS1 (0.39) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130184343-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-07-18 | — | — | US | disclosed |
| US-20130184343-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-07-18 | — | — | US | disclosed |
| US-20130184343-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-07-18 | — | — | US | disclosed |
| US-8420855-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-16 | — | — | US | disclosed |
| US-8420855-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-16 | — | — | US | disclosed |
| US-8420855-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-16 | — | — | US | disclosed |
| US-20100048715-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| US-20100048715-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| US-20100048715-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| WO-2008000438-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048715-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, CHRM2 | JAK2 4085/4885JAK1 4559/4885EPHX2 484/4885 |
| US-20130184343-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, CHRM2 | JAK2 4089/4885JAK1 4563/4885EPHX2 488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.