Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.49 |
| ▸ | JAK1 | P23458 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 13/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3211745 | 0.85 | JAK2 (0.40) | JAK2JAK1RXFP1MAPTP2RX1 | |
| SCHEMBL3212463 | 0.81 | RORC (0.48) | POLBMAPTP2RX1 | |
| SCHEMBL14849969 | 0.81 | ALDH1A1 (0.43) | JAK1RXFP1MAPTP2RX1 | |
| SCHEMBL27785087 | 0.81 | MEN1 (0.50) | POLBMAPT | |
| SCHEMBL1842740 | 0.78 | RXFP1 (0.42) | RXFP1PTGESPOLBMAPTKDR | |
| SCHEMBL13455970 | 0.78 | LMNA (0.43) | MAPT | |
| SCHEMBL27833488 | 0.78 | RXFP1 (0.45) | RXFP1POLBP2RX1 | |
| SCHEMBL27953249 | 0.78 | PDK1 (0.43) | RXFP1PTGESPOLBMAPTP2RX1 | |
| SCHEMBL19240705 | 0.77 | PDK1 (0.42) | RXFP1PTGESPOLBMAPTP2RX1 | |
| SCHEMBL15429520 | 0.77 | POLB (0.48) | RXFP1POLBMAPTP2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103408453-A | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG | 2013-11-27 | — | — | CN | disclosed |
| US-20130184343-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2013-07-18 | — | — | US | disclosed |
| US-8420855-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-16 | — | — | US | disclosed |
| US-20100048715-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| EP-2044006-A1 | INSECTICIDAL COMPOUNDS | Syngeta Participations AG (CH) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008000438-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048715-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, CHRM2 | JAK2 4085/4885JAK1 4559/4885RXFP1 1992/4885 |
| US-20130184343-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, CHRM2 | JAK2 4089/4885JAK1 4563/4885RXFP1 2047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.