Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.62 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | DRD4 | P21917 | 3/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP5 | P51878 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SMO | Q99835 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3619267 | 0.80 | ALDH1A1 (0.61) | ALDH1A1MAPTNPBWR1MCHR1L3MBTL1 | |
| SCHEMBL2744707 | 0.80 | ALDH1A1 (0.61) | ALDH1A1MAPTNPBWR1MCHR1L3MBTL1 | |
| SCHEMBL12659901 | 0.80 | LMNA (0.61) | ALDH1A1MAPTNPBWR1MCHR1L3MBTL1 | |
| SCHEMBL20804885 | 0.80 | MAPT (0.61) | ALDH1A1MAPTNPBWR1MCHR1L3MBTL1 | |
| SCHEMBL4392263 | 0.80 | DRD4 (0.70) | ALDH1A1MAPTDRD4SIGMAR1HTR7 | |
| SCHEMBL844318 | 0.80 | KDM4E (0.56) | ALDH1A1MAPTNPBWR1MCHR1L3MBTL1 | |
| SCHEMBL1540132 | 0.79 | HTR7 (0.52) | ALDH1A1MAPTDRD4HTR7DRD2 | |
| SCHEMBL3211217 | 0.78 | ME2 (0.52) | ALDH1A1MAPTNPBWR1MCHR1L3MBTL1 | |
| SCHEMBL3211194 | 0.78 | ME2 (0.52) | ALDH1A1MAPTNPBWR1MCHR1L3MBTL1 | |
| SCHEMBL6704714 | 0.77 | ALDH1A1 (0.97) | ALDH1A1MAPTNPBWR1MCHR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962674-B2 | Curcumin derivative | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2015-02-24 | — | — | US | disclosed |
| US-20100048901-A1 | NOVEL CURCUMIN DERIVATIVE | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2010-02-25 | — | — | US | disclosed |
| EP-2123637-A1 | NOVEL CURCUMIN DERIVATIVE | Tokyo Institute of Technology (JP) | 2009-11-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048901-A1 | NOVEL CURCUMIN DERIVATIVE | BACE1, APP, BACE2 | ALDH1A1 253/4885MAPT 8/4885NPBWR1 485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.